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Anterior Segment Changes After Pars Plana Vitrectomy With SO Using AS-OCT

Anterior Segment Changes After Pars Plana Vitrectomy With Silicone Oil Tamponade And After Silicone Oil Evacuation Using AS-OCT.

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06524661
Enrollment
30
Registered
2024-07-29
Start date
2023-04-15
Completion date
2024-04-15
Last updated
2024-07-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glaucoma

Keywords

ASOCT, Glaucoma, Silicone, vitrectomy, angle

Brief summary

To evaluate changes in ACA induced by pars plana vitrectomy with SO 1000cs injection in vitreo-retinal surgery in phakic eyes using AS-OCT and changes in the IOP preoperatively, post-operatively and post-silicone oil evacuation.

Detailed description

Abstract Introduction Ocular hypertension and secondary glaucoma are relatively common and serious complications in silicone filled eyes which may end in blindness. Reports have described the percentage of incidence to be within 3 - 30 % of silicon filled eye which are complicated with secondary glaucoma. \[1\] Aim of study Evaluation of changes in anterior chamber angle and intra-ocular pressure (IOP) in patients with rhegmatogenous retinal detachment (RRD) who underwent pars plana vitrectomy (PPV) with silicone oil (SO) 1000cs tamponade and after silicone oil evacuation. Population The study was a prospective interventional study. The study included 30 eyes from 30 patients with rhegmatogenous retinal detachment (RRD) who are going to undergo PPV with SO injection. The study was conducted at Ophthalmology department, Minia University Hospital in Egypt between April 2023 and April 2024.

Interventions

DEVICEAS-OCT after vitrectomy

AS-OCT is a light based imaging technique of the anterior segment of the eye in this study it is used to measure the anterior chamber angle changes after pars plana vitrectomy.

Sponsors

Minia University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
16 Years to 75 Years
Healthy volunteers
No

Inclusion criteria

* • Patients with rhegmatogenous retinal detachment who are going to undergo vitreoretinal surgery with silicone oil 1000cs injection as tamponade

Exclusion criteria

* Patients with history of intraocular surgery, laser therapy or intravitreal injection. * Patients with significant corneal opacity. * Patients with ocular diseases as retinal vein occlusion, uveitis and proliferative diabetic retinopathy. * Patients with preexisting glaucoma or family history of glaucoma. * Patients with nystagmus. * Patient with tractional retinal detachment, exudative retinal detachment or intraocular foreign body. * Patients with anterior chamber abnormalities including posterior synechia, peripheral anterior synechia, hyphaema and iris abnormalities. * Patients with severe proliferative vitreoretinopathy grade C or more.

Design outcomes

Primary

MeasureTime frameDescription
Assessement of the changes in anterior chamber angle after vitrectomy with silicone oil injectionpostoperative evaluation for 3 months duration (5 visits pre-ppv then one week, one month, three months )Evaluation of changes in the anterior chamber angle parameters after vitrectomy with silicone oil 1000cs injection. The measures include AOD 500, TISA 500, ACA and CCT The measuring tool is AS-OCT (anterior segment optical coherent topography)

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026