Liver Tumor
Conditions
Keywords
liver tumors, benign, malignant, Differential diagnosis
Brief summary
To explore an effective noninvasive method for differential diagnosis of liver tumors.
Detailed description
A retrospective study was performed to assess the performance of certain ultrasound-based parameters, in distinguishing benign from malignant with liver biopsy as the gold standard. Demographic data, clinical information and serological data were obtained from participants who were retrospectively enrolled. Receiver operating characteristic (ROC) curve analysis was conducted, including calculation of the optimal area under the ROC curve (AUC), to assess the performance of these measures in distinguishing between benign and malignant in patients with or without chronic liver disease.
Interventions
DIAGNOSTIC_TESTwith chronic liver disease
patients with hepatitis B virus，hepatitis C virus, or other chronic liver disease
Sponsors
Xijing Hospital
Study design
Observational model
OTHER
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
(1) age 18-70 years; (2) liver examination performed for all patients prior to US-guided liver biopsy or surgery; (3) tumor can be visualized in conventional US; (4) largest tumor sectional area saved in DICOM format for use in later analyses; (5) a histopathological diagnosis made either from US-guided liver biopsy or surgical resection; (6) suitable routine clinical and US data obtained within 7 days of the histopathological diagnosis.
Exclusion criteria
(1) unavailable pathological diagnosis; (2) liver metastatic tumors; (3) poor quality US images; and (4) a past history of surgical resection, percutaneous local ablation, radiation, transarterial and systemic therapies or liver transplantation.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The differential diagnosis of liver tumors | 2018.01-2025.12 | Multimodal ultrasound is of great value in the differential diagnosis of liver tumors |
Countries
China
Contacts
Primary ContactZhou Huihui, M.M.
Outcome results
None listed