Acne Scars - Atrophic
Conditions
Brief summary
in a split face fashion, 30 patients will be randomized into 3 groups: Group A: rt side treated with SVF enriched PRP, lt side treated with prp Group B: rt side treated with SVF enriched PRP, lt side treated with SVF Group C: rt side treated with PRP, lt side treated with SVF
Interventions
BIOLOGICALStromal vascular fraction (SVF) enriched platelet rich plasma (PRP) versus each alone
Adipose derived stromal vascular fraction cells will be aspirated and isolated from patient autologous adipose tissue and used to enrich patient's autologous platelet rich plasma then will be used to treat atrophic post acne scars versus each alone.
Sponsors
Zagazig University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* patients with atrophic post acne scars without any previous treatment trials. * adequate blood picture, no anemia, no bleeding or platelet disorders.
Exclusion criteria
* pregnant and lactating females. * elderly. * patients with bleeding tendencies.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| change in severity of acne scars using Goodman scoring system | 3 monthly sessions and follow up for 3 months after the last visit | at baseline, acne scars will be assessed clinically using the 4 point grading system proposed by Goodman &colleagues in 2006, patients' complaints and expectations will be addressed as well and the impact of acne scars on patients' quality of life will be investigated using the dermatology life quality index (DLQI). Goodman scoring system will be used at the last session and at the follow up visit to measure the change pre and post treatment. |
Countries
Egypt
Outcome results
None listed