Periodontal Pocket
Conditions
Brief summary
The current study is a prospective randomised study-Comparison of photodisinfection with chitosan nanoparticles enriched indocyanine green over indocyanine green as an adjunct to open flap debridement in the management of stage II/III grade B/C periodontitis.
Detailed description
A total of 24 patients fulfilling inclusion criteria will be randomly assigned into two treatment groups (Test and Control). Open flap debridement followed by photodynamic therapy using dyes is carried out. Test group (n=12) - PDT with Chitosan nanoparticles enriched ICG Control group(n=12) - PDT with ICG Microbial levels of P.gingivalis is analysed with PCR analysis on baseline and 3 months after intervention.
Interventions
PROCEDUREPHOTODYNAMIC THERAPY
Respective photosensitive dye solution is applied on to the surgical site, including all the root surfaces. Vacuum suction is used to remove the excess dye from the site and to prevent ingestion of the dye solution The dye is activated with 810nm diode laser with continuous wave frequency and power of 0.3 W with 400 µm fiber tip for 20 seconds/spot. After this, the area is irrigated with saline.
Sponsors
Krishnadevaraya College of Dental Sciences & Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
30 Years to 55 Years
Healthy volunteers
Yes
Inclusion criteria
* Systemically healthy subjects * Age group 30-55yrs. * Diagnosed with Stages II/III grade B/C periodontitis. * Presenting with persistent pocket depth ≥5mm after initial non-surgical therapy. * Optimal plaque control * Good compliance
Exclusion criteria
* Subjects on antibiotic therapy within last six months of enrollment * Previous history of periodontal surgery * Allergy to drugs and materials used in this study * Pregnant woman * Subjects with deleterious habits like smoking, tobacco chewing.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| MICROBIAL ANALYSIS | 3 MONTHS | LEVELS OF P. GINGIVALIS |
Contacts
Primary ContactDR.PRABHUJI MLV, MDS
Backup ContactDR.MEGNA KM, MDS
Outcome results
None listed