Constipation, Impaction, and Bowel Obstruction, Obstructed Defecation Syndrome, TAMIS Mucosectomy
Conditions
Keywords
obstructed defecation syndrome, TAMIS mucosectomy
Brief summary
Patients, aged 18 - 90 years, undergoing TAMIS mucosectomy at the Department of General Surgery at the Medical University of Vienna are enrolled into our study. Primary endpoint is the outcome (improvement of ODS symptoms), defined by ODS score.
Detailed description
Various surgical approaches for the treatment of obstructed defecation syndrome (ODS) commonly associated with rectocele and rectal intussusception have been investigated in the literature. Methods such as stapled transanal resection of the rectum (STARR) and ventral prosthesis rectopexy (VPR) show promising results at least in the short term. In the long-term, however, the results do not seem convincing. Schiano di Visconte et al. report a recurrence of ODS symptoms in 40 percent of the patients, treated with stapled transanal rectal resection in a 10-year follow up. The clinical outcome of surgical treatment of ODS using transanal minimally invasive surgery (TAMIS) in the sense of a mucosal resection without stapling technique has not yet been investigated. This project is designed to show the short-term outcome of non-stapled mucosal resection through TAMIS.
Interventions
PROCEDURETAMIS mucosectomy
internal Delorme's procedure using TAMIS
Sponsors
Medical University of Vienna
Study design
Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* Need of minimal invasive mucosal resection due to obstructed defecation syndrome after several unsuccessful conservative treatments over a period of more than 6 months with presence of an organic cause (Symptomatic intussusception with or without rectocele) in medical examinations (defecography, endoluminal ultrasound, endoanal manometry) * Age: 18-90 years * Ability and willingness to understand and comply with planned interventions during the study. * Voluntarily signed informed consent after a full explanation of the study to the participant.
Exclusion criteria
* Any physical or mental disorder could interfere with the participant's safety during the clinical trial or with the study objectives. * Inability to communicate well with the investigator due to language problems or reduced mental development. * Inability or unwillingness to give written informed consent.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| functional outcome assessment | 6 months | functional outcome defined by ODS score |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| fecal incontinence assessment | 6 months | fecal incontinence improvement or worsening measured by using the VAIZEY Score |
| Quality of life assessment | 6 months | Health-related quality of life after TAMIS in ODS patients, defined by Quality of Life Score (SF12). |
Countries
Austria
Outcome results
None listed