Cognition
Conditions
Keywords
transcutaneous electrical acupoint stimulation, cognition, hypoxia
Brief summary
Cognitive impairment is common in people who suffer from hypoxia. Acupuncture and related techniques can be used to improve hypoxia and treat cognitive impairment. In this trial the effect of transcutaneous electrical acupoint stimulation on cognitive impairment in people under hypoxia will be investigated.
Interventions
OTHERtranscutaneous electrical acupoint stimulation
Electrodes are placed at acupoints and connected to the stimulator. Electrical stimulation is given for 2 hours.
Sponsors
Zhihong LU
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
DOUBLE (Investigator, Outcomes Assessor)
Masking description
The stimulator is put in an opaque box
Eligibility
Sex/Gender
MALE
Age
18 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* Male, age from 18 to 50 years
Exclusion criteria
* cardiopulmonary dysfunction; * History of severe respiratory, circulatory, digestive, blood, ear-nose-throat system diseases; * A history of fever or respiratory infection within the last two weeks; * Drinking alcohol or poor sleep within the last 24 hours
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cognitive function measured by eye-tracking at 1 hour after hypoxia | 1 hour after hypoxia |
| cognitive function measured by eye-tracking at 2 hours after hypoxia | 2 hours after hypoxia |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| saturation of pulse oximetry | starting from 10 minutes before hypoxia to 2 hours after hypoxia, every 5 minutes for 2 hours and 10 minutes | — |
| Cerebral oxygen saturation | starting from 10 minutes before hypoxia to 2 hours after hypoxia, every 5 minutes for 2 hours and 10 minutes | — |
| total sleep time on the first day after hypoxia | the first day after hypoxia, in a total of 24 hours | — |
| heart rate | starting from 10 minutes before hypoxia to 2 hours after hypoxia, every 5 minutes for 2 hours and 10 minutes | — |
| number of awake on the first day after hypoxia | the first day after hypoxia, in a total of 24 hours | — |
| time of awake on the first day after hypoxia | the first day after hypoxia, in a total of 24 hours | — |
| sleep efficiency(%) on the first day after hypoxia | the first day after hypoxia, in a total of 24 hours | sleep efficiency=total sleep time/total recording time |
| mean arterial blood pressure | starting from 10 minutes before hypoxia to 2 hours after hypoxia, every 5 minutes for 2 hours and 10 minutes | — |
Countries
China
Contacts
Primary ContactZhihong Lu
Outcome results
None listed