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Periapical Lesions and Immediate Implants

Immediate Implant Placement in Sites With Chronic Periapical Lesions

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06521203
Enrollment
25
Registered
2024-07-25
Start date
2016-01-01
Completion date
2023-12-01
Last updated
2024-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental Implant Failure Nos, Osseointegration Failure of Dental Implant, Periapical Granuloma

Keywords

Dental implant, Immediate dental implant, Osseointegrated implants, Osseointegration, Periapical granuloma, Tooth extraction

Brief summary

The aim of this case-control study is to evaluate the success and survival rates of dental implants immediately placed into extraction sites in the presence of periapical pathology. The main questions it aims to answer are: What were the survival and success rates of implants immediately placed into extraction sockets of teeth with chronic periodical lesions. A retrospective analysis was performed based on the evaluation of certain clinical and radiographic parameters 12 months after prosthetic function of these implants.

Detailed description

In 25 patients (13 men, 12 women), certain clinical and radiological parameters were retrospectively evaluated with particular interest in survival and success rates of the implants (total of 30 implants, 21 in the maxilla, 9 in the mandible) placed immediately to extraction sites of teeth with chronic periapical lesions. These parameters included mobility and the presence or absence of chronic pain, probing depth, gingival index, radiographic measurements of crestal bone loss on mesial and distal aspects of the implants.

Interventions

None listed

Sponsors

Akdeniz University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* To have 1 or more teeth with a chronic periapical lesion that requiring extraction. * The chronic periapical lesion should be determined as an asymptomatic periapical radiolucency with a diameter ranging between 4 and 8 mm. * The patients undergoing tooth extraction must have been treated with an immediate implant placement procedure. * At the time of extraction and implant placement, the neighboring teeth must have had healthy periodontal and periapical status.

Exclusion criteria

* Age younger than 18 years * Any systemic disease or medication that might compromise osseointegration, bone or soft tissue healing * Smoking * Purulent exudate during the extraction * Severe deficiency of soft and/or hard tissue in implant region * Pregnancy * Lactation * History of chemotherapy or radiotherapy * Severe parafunctional habits

Design outcomes

Primary

MeasureTime frameDescription
Survival of the implantsImmediately after the implant placement and after 12 months of prosthesis function.Pain on palpation, percussion, or function (Yes/No) Implant mobility (Yes/No) Radiographic crestal bone loss (\<4.0 mm) Absence of pain and mobility and crestal bone loss up to 4 mm were regarded as survive.
Success of the implantsImmediately after the implant placement and after 12 months of prosthesis function.Pain on palpation, percussion, or function (Yes/No) Implant mobility (Yes/No) Radiographic crestal bone loss (\<2mm) Gingival index score (1-2-3) Probing depth (mm) Absence of pain and mobility, crestal bone loss \<2mm, GI score less than 2, probing depth \<5mm were regarded as success.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026