Minimal Flow Anesthesia, Low Flow Anesthesia, Robotic Assisted Laparoscopic Abdominal Surgery
Conditions
Brief summary
This study aims to compare the use of low fresh gas flow (1 L/min) desflurane anesthesia with minimum fresh gas flow (0.5 L/min) desflurane anesthesia in patients undergoing robotic-assisted abdominal surgery. The comparison will be based on hemodynamic and respiratory parameters. The secondary aim of our study is to compare the two different fresh gas flow methods in terms of inhalation agent consumption and soda lime consumption.
Interventions
OTHERblood gas analysis
1. Airway pressure (P plateau, Ppeak) values are taken from the anesthesia device data, 2. BIS (from routine BIS monitoring) 3. Temperature (routinely from pharyngeal temperature probe), 4. Oxygen saturation (routinely from the patient monitor) 5. End-tidal CO₂, 6. inspiratory O₂ concentration, 7. Inspiratory CO2 concentration, 8. inspiratory and expiratory desflurane concentrations, 9. tidal volume, 10. MAC is routinely obtained from anesthesia device data. 11. Blood Gas Analysis (COHgb, Ph, PO2, PCO2, SaO2, HCO3, Base deficit, glucose, lactate)
Sponsors
Ankara City Hospital Bilkent
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
* Patients undergoing robotic-assisted abdominal surgery
Exclusion criteria
* serious cardiac, respiratory, hepatic, renal, or mental disorders; * hearing problems; * anxiety, depression, or other psychiatric conditions; * patient's request to leave the study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| inspiratory O2 concentration | from beginning of anesthesia induction to the end of anesthesia (during periopertaive period) | inspiratory O2 concentration is measured from anesthesia machine monitor |
| partial oxygen pressure | from beginning of anesthesia induction to the end of anesthesia (during periopertaive period) | PO2 from blood gas analysis |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| desflurane consumption | 3th hour | desflurane consumption |
| changes in liver and kidney function tests from the preoperative values to 48 hours postoperative | postoperative 1st day | to determine the changes in serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), blood urea nitrogen (BUN), and creatinine from the preoperative values to 48 hours postoperative |
Countries
Turkey (Türkiye)
Contacts
Primary ContactBetül Güven Aytaç
Outcome results
None listed