The Effect of Injectable PRF Vs LLL on Orthodontic Tooth Movement

The Effect of Injectable Platelet Rich Fibrin Versus Low-Level LASER Therapy on The Rate of Orthodontic Tooth Movement

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06520761

Enrollment

Registered

2024-07-25

Start date

2022-11-01

Completion date

2024-12-01

Last updated

2024-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rate of Canine Retraction, Root Resorption

Brief summary

The purpose of the present study is to compare the effect of injectable platelet fibrin and Low Level LASER therapy on the rate of upper canine retraction, and on root resorption of the canine

Detailed description

the study involves two groups the first group received low level laser at the upper right canine, while the upper left canine act as a control. The second group received injectable platelet rich fibrin at the upper right canine, while the upper left canine act as a control. in each group we will compare rate of canine retraction between both sides, and amount of root resorption also we will compare both groups regarding rate of canine retraction and amount of root resorption

Interventions

PROCEDUREInjectable platelet rich fibrin

blood sample obtained from the participant, centrifuged at 700 rpm to produce injectable platelet rich fibrin, this will be injected around the upper canine

DEVICELow Level LASER

Diode LASER device is used to apply Low Level LASER around the upper canine

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

OTHER

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 25 Years

Healthy volunteers

Yes

Inclusion criteria

1. Patients with age 18 years or older. 2. Presence of all permanent teeth except for the third molar. 3. Presence of malocclusion requiring maxillary first premolar extraction such as (class II division 1 or bimaxillary dentoalveolar protrusion).

Exclusion criteria

1. Patient with a history of previous orthodontic treatment. 2. Medical problems may interfere with orthodontic treatment. 3. Bad oral hygiene.

Design outcomes

Primary

Measure	Time frame	Description
Rate of canine retraction	4 month	measure the rate of distal movement of the upper canine

Secondary

Measure	Time frame	Description
Root resorption of upper canine	4 month	measure root resorption of upper canine

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026