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Third Molars Extraction and Periodontal Disease

Correlation Between Upper Third Molars Extraction and Upper Second Molars Periodontal Disease: a Prospective Clinical Observational Study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06520137
Enrollment
126
Registered
2024-07-25
Start date
2024-03-27
Completion date
2026-09-15
Last updated
2024-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontal Diseases

Brief summary

The aim of the study is to evaluate the changes in periodontal conditions on the distal aspect of the second maxillary molar after the extraction of the maxillary wisdom tooth. As secondary outcome patient- related and tooth-related factors will be analysed to evaluate their effects on the periodontal varibales during time.

Interventions

PROCEDURETooth extraction

Extraction of maxillary third molars

Sponsors

Azienda Ospedaliera Universitaria Senese
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
19 Years to 64 Years

Inclusion criteria

* Age more than 18 years or older * Presence of an impacted upper wisdom tooth that need to undergo surgical extraction * Participants need to be able to sign and understand the informed consent and to follow the study-related procedures.

Exclusion criteria

* People that have compromised general health conditions (ASA 3, 4, 5, 6) * Patients that assumed antibiotics in the last 6 months * Pregnant or breastfeeding women * Patients who suffer from periodontitis stage III and IV * Presence of a third molar with incomplete root formation is not taken into account for the surgical extraction. * Smoker patients

Design outcomes

Primary

MeasureTime frameDescription
Probing Pockeet Depth (PPD)Baseline, 1 month, 6 months, 12 months, 24 monthsDistance between the free gingival margin and the apical location of the probe's tip.
Bone Level (BL)Baseline, 1 month, 6 months, 12 months, 24 monthsDistance between the bone crest and the cemento-enamel junction (CEJ)

Secondary

MeasureTime frameDescription
Type of impactionBaselineAccording to Archer's classification it is possible to have seven types of impaction: mesio-angular, disto-angular, bucco-angular, linguo-angular, horizontal, vertical, inverted.
Clinical Attachment Level (CAL)Baseline, 1 month, 6 months, 12 months, 24 monthsDistance between the cemento-enamel junction and the apical location of the probe's tip
Recession (REC)Baseline, 1 month, 6 months, 12 months, 24 monthsDistance between the free gingival margine and the cemento-enamel junction (CEJ)
Keratinized Tissue (KT)Baseline, 1 month, 6 months, 12 months, 24 monthsDistance between the muco-gingival line and the free gingival margin

Countries

Italy

Contacts

Primary ContactChiara Malpassi
chiara.malpassi@gmail.com+ 39 3331375702
Backup ContactSimone Grandini
grandini@unisi.it+39 3357045335

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026