SprmPik AI Sperm Selection Study SiD, an Assistant for Sperm Selection During Intracytoplasmic Sperm Injection in Medically Assisted Reproduction: Effect on Fertilization, Blastocyst Formation, Early Pregnancy Loss, and Consistent Practice. A Prospective Pilot Study.

SprmPik AI Assisted Sperm Selection Study, an Assistant for Sperm Selection During ICSI

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06518928

Acronym

SprmPik

Enrollment

155

Registered

2024-07-25

Start date

2024-01-01

Completion date

2026-10-01

Last updated

2024-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Brief summary

SprmPik AI Assisted Sperm Selection Study SiD, an assistant for sperm selection during intracytoplasmic sperm injection in medically assisted reproduction: effect on fertilization, blastocyst formation, early pregnancy loss, and consistent practice. A prospective pilot study.

Detailed description

The purpose of this research is to evaluate the impact of sperm selection for ICSI using the investigational SiD software, on performance outcomes such as the rate of fertilization, blastocyst development, clinical pregnancy success, and other intermediate results, in a pilot study. SiD is a software designed to identify, evaluate, and assist in the sperm selection process within a semen sample, according to motility (for instance velocity, linearity, straightness) patterns and the shape of the sperm. SID uses a mathematical model. Its purpose is to assist clinical embryologists in selecting sperm to inject during ICSI. Currently, embryologists identify and select sperm based on the sperm motility and shape; not using any mathematical interphase assistant.

Interventions

OTHERArtificial Intelligence assisted sperm selection

SiD software for sperm selection

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Yes

Inclusion criteria

for Male Partner (sperm source) * Informed consent signed by the patient before treatment. * IVF treatments with medical or embryology indication to perform ICSI. * Fresh or frozen ejaculated motile sperm. * Selection of sperm using a 7% or 10% PVP solution. * Presence of motile sperm at the time of sperm selection for ICSI. * Partner sperm

Exclusion criteria

for Male Partner (sperm source) * Sperm extracted by testicular biopsy. * That the recommendations for use of SiD have not been fully followed. * Inability to reliably trace sperm-oocyte-embryo throughout the process. * Patients with immotile sperm Inclusion criteria for Female Partner (egg source) * Informed consent signed by the patient before treatment. * IVF treatments with medical or embryology indication to perform ICSI. * Cycles with at least 4 mature oocytes (Metaphase II). * Fresh or frozen oocytes.

Design outcomes

Primary

Measure	Time frame	Description
Oocyte Fertilization	1 day	Does SiD assist in ICSI Fertilization

Secondary

Measure	Time frame	Description
Blastocyst Formation	7 days	Do embryos develop better from SiD oocytes

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026