Acute Respiratory Distress Syndrome, Prone Positioning, SARS-CoV 2 Pneumonia
Conditions
Brief summary
Retrospective single center study on the effect of awake prone positioning in ICU patients with severe hypoxemia related to SARS-COV2
Detailed description
Retrospective, observational study on the effects of awake prone positioning on oxygenation, invasive mechanical ventilation requirement and mortality in non intubation patients with severe hypoxemia related to SARS-COV2 and regardeless of the oxygen supplementation method.
Interventions
PROCEDUREProne positioning
Prone positioning sessions: at least one session per day proning duration: 2 hours at least per session
Sponsors
Mongi Slim Hospital
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* All adult (\> 18 years) patients, non intubated, with acute respiratory failure due to COVID-19 pulmonary infection
Exclusion criteria
* patients: hemodynamic instability and high doses of vasopressors * patients with contraindications of prone positioning: pregnancy, recent abdominal surgery * patients with pulmonay embolism * patients requiring invasive mechanical ventilation for extra respiratory reasons: neurological failure, urgent surgery
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Intubation | at day 7 | invasive mechanical ventilation requirement |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| ICU mortality | at Day 14 | observed mortality rate in the ICU |
Countries
Tunisia
Outcome results
None listed