Type 2 Diabetes
Conditions
Keywords
Moringa oleifera, Type 2 diabetes, Humans, Glucose, HbA1c
Brief summary
The objective of this clinical trial was to understand whether supplementation of Moringa oleifera leaf powder improved glycemic management in Sahrawi women with type 2 diabetes living in refugee camps. The main question sought to be answered was: \- Does daily supplementation of Moringa oleifera leaf powder, in addition to oral hypoglycemic therapy, improve glycosylated hemoglobin and fasting blood glucose? Researchers compared Moringa supplementation with no Moringa consumption to see if Moringa oleifera worked to improve glycemic control. Participants had to: * Take Moringa oleifera leaves daily or abstain from consuming Moringa for 3 months. * Consistently take prescribed oral hypoglycemic agents * Undergo clinical examinations and measurement of biochemical, metabolic and body composition parameters at the time of recruitment and at the end of the study.
Interventions
DIETARY_SUPPLEMENTSupplementation of Moringa oleifera leaf powder
Women in the experimental group were asked to consistently take the prescribed oral hypoglycemic therapy and to maintain their lifestyle and eating habits. In addition, for the duration of the study (3 months), the experimental group was provided with 10 g of Moringa oleifera leaf powder daily to be consumed with main meals.
Sponsors
University of Milan
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Diagnosis of type 2 diabetes for at least 1 year * Absence of advanced retinopathy, terminal renal failure, active diabetic ulcers, amputations, and heart failure * Treatment with only oral hypoglycemic drugs.
Exclusion criteria
* Diagnosis of type 1 diabetes * Pregnancy or lactation * Treatment with insulin.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glycosylated hemoglobin (HbA1c) | Glycosylated hemoglobin was measured at recruitment and at the end of the study (three months) |
| Fasting glucose | Fasting glucose was measured at recruitment and at the end of the study (three months) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Hip circumference | Hip circumference were measured at recruitment and at the end of the study (3 months) | — |
| BMI | BMI were measured at recruitment and at the end of the study (3 months) | — |
| Blood pressure | Systolic and diastolic blood pressure were measured at recruitment and at the end of the study (3 months) | Systolic and diastolic blood pressure |
| % body fat | % of body fat were measured at recruitment and at the end of the study (3 months) | — |
| Waist circumference | Waist circumference were measured at recruitment and at the end of the study (3 months) | — |
Countries
Algeria
Outcome results
None listed