Elective Cardiac Surgery
Conditions
Keywords
Parasternal block, Cardiac surgery, Serum lactate
Brief summary
Serum lactate level is a key indicator of tissue perfusion. Parasternal blockade is associated with reduced postoperative inflammatory response by inhibiting stress response, leading to better outcomes. Elevated lactate levels help identify patients at risk of postoperative morbidity and mortality. This analytical cross-sectional study evaluated the association between parasternal blockade and serum lactate levels in patients undergoing elective cardiac surgery in 2022 at Specialty Hospital CMNO. Patients with and without parasternal block were compared for changes in serum lactate levels during and after anesthesia within the first 24 hours.
Detailed description
Background: Serum lactate level is a crucial indicator of tissue perfusion. Parasternal blockade has been related to a reduction of the postoperative inflammatory response, by inhibition of the stress response, leading to a better prognosis. Increased lactate level is a useful parameter in the identification of patients at risk of postoperative morbidity and mortality. Objective: To evaluate the association between parasternal blockade and serum lactate level in patients undergoing cardiac surgery, both trans and postanesthesia. Materials and Methods: Analytical cross-sectional study in adult patients undergoing elective cardiac surgery during the year 2022 in Specialty Hospital CMNO, patients with and without application of parasternal block were analyzed, and it was associated with changes in serum lactate level trans and post anesthesia in the first 24 hours. Approval registration: R-2023-1301-024.
Interventions
PROCEDUREParasternal block
In the case-control groups, patients with elevated serum lactate levels above 2 mmol/L and those who remained below this limit will be identified.
PROCEDURERequirement of total dose regarding fentanyl
In case-control groups, obtain measurement of total postoperative fentanyl requirement.
Sponsors
Instituto Mexicano del Seguro Social
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Intervention model description
Patients will be classified into a case group with parasternal block and a control group without parasternal block, with a ratio of cases to controls of 1:1. In the case-control groups, patients with elevated serum lactate levels above 2 mmol/L and those who remained below this limit will be identified.
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adult patients older than 18 years * Either sex * ASA II-III * Patients who underwent cardiac surgery with median sternotomy and use of cardiopulmonary bypass.
Exclusion criteria
* Patients with pre-existing conditions that could independently affect serum lactate levels.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Serum lactate measurement | 24 hours postoperative | Elevated serum lactate levels above 2 mmol/L |
Countries
Mexico
Contacts
Primary ContactAlejandro Gonzalez, 3
Backup ContactClotilde Fuentes, 1
Outcome results
None listed