Screening Tool for Malnutrition, Sarcopenia, and Cachexia

Development and Validation of a New Tool for Simultaneous Screening of Malnutrition, Sarcopenia, and Cachexia in Older Adults

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06516367

Acronym

ASUST-MSC

Enrollment

300

Registered

2024-07-23

Start date

2023-06-01

Completion date

2024-04-30

Last updated

2024-07-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cachexia, Malnutrition, Sarcopenia

Keywords

screening, older adult, malnutrition, cachexia, sarcopenia

Brief summary

There is an accumulating evidence of the overlap and frequent co-occurrence of twasting conditions in older adults. Those conditions include malnutrition, sarcopenia, and cachexia, Therefore , a tool capable of simultaneously screening for all three conditions is imperative. In this study, we developed and validated a new tool for the simultaneous screening of muscle wasting diseases in older adults. The diagnostic accuracy of the new tool was compared to other validated screening tools including the Mini Nutritional Assessment-Short Form (MNA-SF), the Short Nutritional Assessment Questionnaire (SNAQ), and the Simple Questionnaire to Rapidly Diagnose Sarcopenia (SARC-F).

Interventions

OTHERAin Shams University Screening Tool for Malnutrition, Sarcopenia, and Cachexia (ASUST-MSC)

25 items dichotomous questionnaire

Study design

Observational model

OTHER

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

65 Years to No maximum

Inclusion criteria

* Participants Aged 65 years and older, who agree to participate

Exclusion criteria

* Patients with critical illness. * Patients with severe cognitive, hearing or visual impairment hindering proper communication * Patients with physical disability that interfere with physical performance assessment or hand grip measurement * Patient with any contraindication of to the use of BIA) e.g. presence of a pacemaker, other implanted electrical devices, or metal implants, volume overload

Design outcomes

Primary

Measure	Time frame	Description
reliability of a new tool for the simultaneous screening of muscle wasting diseases in older adults	10 months	Relaibility; Cronbach's alpha coefficient was used to evaluate the internal consistency.
validity of a new tool for the simultaneous screening of muscle wasting diseases in older adults	10 months	Validity; Spearman's correlation coefficient was used to examine construct validity of the new tool

Secondary

Measure	Time frame	Description
The diagnostic accuracy of the new tool	10 months	The Receiver operating curve was plotted to detect the area under curve of the new tool, for diagnosing muscle wasting diseases.

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026