The Added Value of Bone Microstructure Assessment in the Management of Osteoporotic Bone

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06513442

Acronym

ADVANTAGE BONE

Enrollment

1500

Registered

2024-07-22

Start date

2024-08-01

Completion date

2034-08-01

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoporosis

Brief summary

1. To assess the clinical utility of trabecular bone score (TBS) on fracture risk prediction including the new version (TBS V4) and future TBS versions at the spine and hip. 2. To assess the clinical utility of TBS software as a potential treatment outcome: sensitivity to change over time and following osteoporosis therapy. 3. To compare TBS to other imaging modalities of bone structure such as quantitative computed tomography (QCT) in fracture risk prediction and response to osteoporosis therapy.

Interventions

OTHERTrabecular bone score software

To assess the clinical utility of trabecular bone score (TBS) on fracture risk prediction including the new version (TBS V4) and future TBS versions at the spine and hip.

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

Has had a DEXA scan * Has had a DEXA scan

Exclusion criteria

* Unable to complete DEXA scan

Design outcomes

Primary

Measure	Time frame
To assess the newest version of TBS software on fracture prediction	10 years

Contacts

Primary ContactClaire Mennan, PhD

claire.mennan@nhs.net0169140

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026