Neurological Disorder
Conditions
Keywords
nutrition, the risk of malnutrition
Brief summary
Neurology disorders are one of the major public health problems that seriously threaten human health. It often accompanied by various nutritional problems, which can aggravate the primary disease, lead to serious complications, prolong the hospitalization, lead to poor prognosis, and increase family and social economic burdens. According to the previous studies, the risk of malnutrition was approximately 58.5% of stroke patients, and 6% had moderate to severe malnutrition in China. Another study conducted in Beijing showed that the risk of malnutrition of elderly patients in the department of neurology was significantly higher than in other departments (28.5% vs. 26.4%). Strengthening nutritional supervision of patients with neurology disorders will benefit to improve patients' prognosis. Therefore, the aim of this study is to investigate the nutritional status of inpatients with neurology disorders in China, evaluate the impact of different nutritional status on patients' health outcomes, and establish a high-quality, standardized nutrition and health cohort database for neurology disorders.
Interventions
None listed
Sponsors
Xuanwu Hospital, Beijing
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Age ≥ 18 years; 2. The primary diagnosis was neurological disorders; 3. Written informed consent.
Exclusion criteria
1. Life expectancy is \< 3 months; 2. Researchers think other ineligible participant for the study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| All-cause mortality | 30 days | Mortality defined as all-cause mortality from inclusion to day 30 |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| ICU admission | 30 days | ICU admission defined as admission to the intensive care unit from the medical ward from inclusion to day 30 |
| Non-elective hospital readmission | 30 days | Non-elective hospital readmission defined as non-scheduled hospital readmission after discharge from the index hospital stay to day 30 |
| Decline in functional status of 10% or more | 30 days | decline in functional status of 10% or more from admission to day 30 measured by the Barthel's index. |
| length of in hospital days | 30 days | Total length of in hospital days 30 days |
| Major complications | 30 days | Major complications defined as the following complications occurring from inclusion (i.e., not present at the time of inclusion) to day 30 I. Adjudicated nosocomial infection or abscess requiring antibiotic treatment II. respiratory failure with need for invasive or non-invasive ventilation III. major cardiovascular events including stroke, intracranial bleeding, cardiac arrest, myocardial infarction with and without invasive procedure and pulmonary embolism IV. acute renal failure (defined by 2x increase of baseline creatinine or new requirement of dialysis do to volume overload or electrolyte disturbance) V. gastro-intestinal events (hemorrhage, intestinal perforation) |
Other
| Measure | Time frame | Description |
|---|---|---|
| Adverse events | 30 days | Each of the adverse events |
Contacts
Primary ContactGaoting Ma, PhD
Outcome results
None listed