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Effects of Core Stabilization and Inspiratory Muscle Training in Patients With COPD

Comparison of the Effects of Core Stabilization and Inspiratory Muscle Training on Diaphragm Activation, Inspiratory Muscle Strength, Functional Capacity, Respiratory Functions, Physical Activity and Quality of Life in Patients With COPD

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06510686
Acronym
COPD
Enrollment
36
Registered
2024-07-19
Start date
2024-10-01
Completion date
2025-06-05
Last updated
2025-09-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Copd

Brief summary

In Chronic Obstructive Pulmonary Disease (COPD), a mismatch develops between the respiratory system's demand and the functional capacity of respiratory muscles due to the combination of local and systemic factors increasing the respiratory workload. This results in impaired coordination of muscle groups, leading to muscle dysfunction. Respiratory muscle dysfunction is a significant determinant of life expectancy in COPD. Additionally, respiratory muscles unable to cope with increased workloads lead to impaired respiratory functions and reduced exercise capacity. It is widely accepted that appropriate training of respiratory muscles can increase their strength, endurance, and their close relationship with lung volume capacities. Besides their role in respiration, respiratory muscles also contribute to postural function and core stabilization. Studies on respiratory muscle training in COPD have primarily focused on inspiratory muscle strength training, neglecting the core stabilization function of respiratory muscles. However, optimal gains in a muscle can only be achieved with training tailored to its functional characteristics. Therefore, a comprehensive training program should be developed considering the multifunctional nature of respiratory muscles. Studies published in healthy individuals and different patient populations demonstrate that core training can improve lung functions. The aim of this study is to compare the effects of inspiratory muscle training and core stabilization training on diaphragm activation, inspiratory muscle strength, functional capacity, respiratory functions, physical activity, and quality of life in individuals with COPD.

Interventions

OTHERİnspiratory muscle training

exercises to strengthen inspiratory muscles

exercises to strengthen inspiratory and core muscles

Sponsors

Mustafa Ertuğrul Yaşa
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
No

Inclusion criteria

* Being over 18 years old * Having a diagnosis of COPD according to the GOLD criteria and being at stage 3 or lower * Not being in an acute exacerbation period and having at least one month since the last exacerbation * Being able to walk independently * Having sufficient mental capacity to understand the tasks in the study (Mini-Mental Test \>24) * Being willing to participate in the study

Exclusion criteria

* Being a stage 4 COPD patient according to the GOLD criteria * Having a diagnosis of lung cancer, pulmonary hypertension, and heart failure * Being in a COPD exacerbation period * Scoring below 24 on the Mini-Mental Test * Having any other disease that affects respiratory functions * Having undergone pulmonary surgery

Design outcomes

Primary

MeasureTime frameDescription
Symptoms8 weeksMMRC Dyspnea Scale (Scores range from 0 to 4)
Respiratory function tests FEV18 weeksSpirometry, FEV1 (lt)
Respiratory function tests FVC8 weeksSpirometry, FVC (lt)
Respiratory function tests PEF8 weeksSpirometry, PEF (lt/sn)
Respiratory function tests FEV1/FVC8 weeksSpirometry, FEV1/FVC %
Respiratory function MVV8 weeksSpirometry, MVV(L/min)
Functional capacity8 weeksSix Minute Walking Test (6MVT) (m)
Inspiratory Muscle Strength8 weeksMaximal Inspiratory Pressure (MIP) (cmH2O),
Inspiratory Muscle Activation8 weekssurface EMG (TLC from FRC (TLC maneuver)(cmH2O)

Secondary

MeasureTime frameDescription
Quality of life Tests8 weekSGRQ (Scores range from 0 to 100)
Core Strength8 week1 minute sit to stand ( how many times sit and stand during 1 minute)
Core Strength flexion8 weekMcgill Endurance Tests For Trunk Flexion (sec)
Core Strength extension8 weekMcgill Endurance Tests For Trunk Extension (sec)
Core Strength side bridge8 weekMcgill Endurance Tests For Side Bridge (sec)
Physical activity,8 weekIPAQ (MET/minute)

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026