Pain Perception Measurement by EEG and NRS

Measuring Pain Perception to the Same Stimulus in Different Patients Using Electroencephalography and Numerical Rate Scale

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06510244

Enrollment

100

Registered

2024-07-19

Start date

2024-01-01

Completion date

2025-04-30

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Electroencephalography, Pain, Toothache

Keywords

pain perception, Numeric Pain Rating Scale, electroencephalography

Brief summary

Observational study at CDI Cleveland Dental Institute. Investigators will assess the pain perception in one group of patients using two non-invasive methods. First, a numerical rate scale (NRS) and second, a brain wave EEG.

Detailed description

To generate the nociceptive stimulus, The investigators will apply cold (Endo-Ice) to a healthy upper incisor tooth #8. Inclusion criteria: Patients between 20 and 60 years old, with healthy teeth, no history of dental alveolar trauma, and no pulp chamber calcification. After the nociceptive stimulus, patients will write their pain perception on paper from 0 to 10, and at the same time, we will record the brain activity with a non-invasive EEG Emotiv. Then, we will correlate both methods.

Interventions

DEVICEEEG EMOTIV

The teeth will be dried with 2x2 gauze; then, Endo Ice will be applied. The patient response will be written on a sheet numbering to choose from 0 to 10, and at the same time, the brain waves will be recorded through EEG.

Study design

Observational model

OTHER

Time perspective

OTHER

Eligibility

Sex/Gender

ALL

Age

20 Years to 60 Years

Inclusion criteria

* Males and females * Age: 20-60 years. * Tooth #8 vital and mature. No history of dentoalveolar trauma. * Adequate coronal tooth structure.

Exclusion criteria

* Chronic periodontitis. * Vertical root fracture. * Immature teeth. * Necrotic teeth. * Systemic diseases that affect the healing process. * Non restorable teeth.

Design outcomes

Primary

Measure	Time frame	Description
Pain Perception Measurement by EEG.	January 2024-December 2024	to observe the brain waves changes during pain perception
Pain Perception Measurement by EEG and NRS.	January 2024-December 2024	To establish a possible correlation between the NRS and EEG measurements.

Countries

United States

Contacts

Primary ContactUlises Carballosa, Resident

u.carballosa@cdiohio.org7866901609

Backup ContactDania Mustafa, Resident

d.mustafa@cdiohio.org5038510616

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026