Sputum
Conditions
Brief summary
600 comatose patients admitted to the hospital in China from June 2024 to June 2028 were randomly divided into groups A and B. Group A used intermittent negative pressure suction through oral and pharyngeal ventilation, while group B used continuous negative pressure suction through regular oral and nasal suction.
Detailed description
Research content: (1) Selection and placement methods of oropharyngeal ventilation tubes, studying the application effects of different models and sizes of oropharyngeal ventilation tubes in critically ill patients, exploring the best placement method to improve the efficiency and safety of sputum suction operations. (2) The norms and techniques of sputum suction, the steps, techniques, and precautions of sputum suction, the depth, strength, time of insertion, and when to interrupt negative pressure, in order to minimize damage to the patient's respiratory mucosa. (3) Evaluation of patient comfort and tolerance, assessing the tolerance and potential adverse reactions of critically ill patients during oral pharyngeal intubation for sputum suction, providing a basis for optimizing sputum suction. (4) Evaluation of sputum suction effect, comparing blood oxygen saturation, respiratory distress, sputum sounds, and other indicators before and after sputum suction to evaluate the effectiveness of sputum suction.
Interventions
PROCEDUREcontinuous negative pressure suction
(1) Open the mouth with a tongue depressor; (2) Apply paraffin oil to the front end of the sputum suction tube; (3) Insert a suction tube into the mouth to aspirate phlegm.
PROCEDUREIntermittent negative pressure sputum suction through oral pharyngeal airway
(1) Insert the oropharyngeal airway parallel into the oral cavity; (2) Apply paraffin oil to the front end of the sputum suction tube; (3) The suction tube is inserted into the deep oral cavity through the middle lumen of the oropharyngeal airway; (4) Intermittent negative pressure for suction and suction of sputum
Sponsors
Affiliated Hospital of Nantong University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
SUPPORTIVE_CARE
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
20 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* 1\. Clinical diagnosis of stroke; 2. Clinical diagnosis of comatose;
Exclusion criteria
* 1\. Clinical diagnosis of multiple organ failure; 2. Clinical diagnosis of multiple organ bleeding;
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Blood oxygen saturation before and after sputum aspiration | Not exceeding 1 day | The degree of binding between oxygen and hemoglobin (Hb) in arterial blood |
| Suctioning time | Not exceeding 2 minute | All time required for sputum suction process |
| Degree of airway bleeding | Not exceeding 30 minute | Use a disposable sputum collection device to aspirate sputum for patients and differentiate the blood content under a blue LED light. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Patient family satisfaction | Not exceeding 1 day | After suctioning, use a satisfaction questionnaire to survey the operating nurses, with a minimum score of 1 and a maximum score of 5. The higher the value, the higher the satisfaction. |
Countries
China
Contacts
CONTACTHonglei Wu, MS
CONTACTYou Lu, BS
STUDY_CHAIRTao Zhang, MD
Ethics Committee of Nantong University Affiliated Hospital
Outcome results
None listed