Breast Cancer, Endotracheal Tube Cuff, Postoperative Sore Throat, Subglottic Airway Injury
Conditions
Keywords
Endotracheal tube cuff, Postoperative sore throat, Subglottic airway injury, Breast Cancer
Brief summary
This study aimed to evaluate the impact of endotracheal tube cuff shapes on the incidence and severity of postoperative sore throat
Detailed description
Postoperative sore throat (POST) is a minor complication after general anesthesia with tracheal intubation but may negatively affect patient satisfaction and postoperative recovery. Due to the multifactorial nature, the detailed mechanism of POST has not been fully understood. However, mucosal irritation and inflammation related to the presence of an ETT within the trachea appear to be one of the primary causes of POST, which may involve elements including the tube size, intracuff pressure, and duration of intubation. In addition, the cuff design of an ETT, which can determine the contact area between the cuff and the tracheal mucosa, is reported to affect the development of POST. This study aimed to evaluate the impact of endotracheal tube (ETT) cuff shapes on the incidence and severity of POST. Additionally, we investigated the influence of ETT cuff shapes on the degree of subglottic injury following GA for breast cancer surgery.
Interventions
DEVICECylindrical-shaped cuff tracheal tube
Tracheal intubation with a cylindrical-shaped cuff tube
DEVICETapered-shaped cuff tracheal tube
Tracheal intubation with a tapered-shaped cuff tube
Sponsors
Tri-Service General Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Female patients scheduled for elective breast cancer surgery performed in the supine position requiring tracheal intubation
Exclusion criteria
* Age \< 18 years or age \> 80 years * Diseases or anatomic abnormalities in the neck, larynx, or pharynx * Combined surgery such as breast reconstruction * Active pulmonary disease * Morbid obesity (body mass index ≥ 40 kg/m2) * Pregnancy * Refusal to join the study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The incidence of postoperative sore throat | Postoperative 48 hours | — |
| The severity of postoperative sore throat | Postoperative 48 hours | 1, none; 2, mild (complains of sore throat only on asking); 3, moderate (complains of sore throat on her own); 4, severe (change of voice or hoarseness, associated with throat pain) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Intraoperative fentanyl consumption | The end of surgery | — |
| Intraoperative propofol consumption | The end of surgery | — |
| Intraoperative rocuronium consumption | The end of surgery | — |
| The degree of subglottic injury | Intraoperative (The time point at extubation) | None: no subglottic injury; mild: mucosal hyperemia and edema and/or slight submucosal hematoma; moderate: moderate submucosal hematoma; severe: mucosal laceration and/or mucosal bleeding) |
Countries
Taiwan
Outcome results
None listed