Acute Kidney Injury, Trehalase Levels
Conditions
Brief summary
We think that in surgical patients requiring hypotensive anesthesia, acute kidney injury, which may occur due to intraoperative renal hypoperfusion, can be diagnosed early by evaluating the urine trehalase value using the ELISA method, and thus, early diagnosed acute renal failure can be treated quickly and patients can be protected from subsequent complications in the postoperative period.
Interventions
DIAGNOSTIC_TESTtrehalase levels
We think that in surgical patients requiring hypotensive anesthesia, acute kidney injury, which may occur due to intraoperative renal hypoperfusion, can be diagnosed early by evaluating the urine trehalase value using the ELISA method
Sponsors
Istinye University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Being over the age of 18 and under the age of 65 * Having signed the BGOF form to be included in the study, * Being in ASA 1 or ASA 2 classification * Not having kidney failure or kidney disease * No history of single kidney or renal transplantation * Not using nephrotoxic drugs or agents before surgery * Renal function tests taken preoperatively should be within normal ranges. * No urinary tract infection or urinary problems (such as polyuria, oliguria or anuria)
Exclusion criteria
* Those under the age of 18 or over the age of 65 * Those who do not want to participate in the study * ASA 3 and above * Having previously received treatment for kidney disease - including kidney stones - * Having been previously diagnosed with acute or chronic renal failure * Having a single kidney or a history of renal transplantation * Using nephrotoxic drugs or agents (such as contrast material) before surgery * Kidney function tests taken preoperatively are not within normal ranges * Having a urinary tract infection or urinary problem (such as polyuria, oliguria or anuria) * Having a history of kidney stones, acute renal failure or chronic renal failure * Those with active infection or disease before surgery * They were determined as patients for whom consent was not obtained for the study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| trehalase levels | 1 month | urine trehalase levels |
Countries
Turkey (Türkiye)
Contacts
Primary Contactilke dolgun
Outcome results
None listed