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Gait Profile Score in Children With Cerebral Palsy (CP): Influence of the CP Type, Treatment With Botulinum Injection and Multilevel Surgery

Gait Profile Score in Children With Cerebral Palsy (CP): Influence of the CP Type, Treatment With Botulinum Injection and Multilevel Surgery

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06505499
Enrollment
51
Registered
2024-07-17
Start date
2024-03-06
Completion date
2024-09-30
Last updated
2025-01-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebral Palsy, Gait Disorders in Children

Keywords

Cerebral palsy, Gait profile score, Botulinum toxin injection, Multilevel surgery

Brief summary

Instrumented three dimensional gait analysis (3DGA) permits to record spatial, temporal, kinetics, kinematics and electromyographic (EMG) parameters in order to understand gait impairment in children and teenagers with cerebral palsy (CP). Nowadays, single-event multilevel surgery in subjects with CP cannot be performed without 3DGA. However, interpretation of multiple and interdependent data remains complex for the clinician. To address this issue, gait statistical index have been developed to give a single measure of the quality of the gait pattern. Among actual index, the Gait Profile Score (GPS), developed by Baker et al (2009), measure the deviation of kinematics parameters from a controlled dataset. The GPS can be divided in nine Gait Variable Score (GVS), corresponding to major lower limb joints: the MAP (Movement Analysis Profile). Many studies have reported the interest of the GPS to analysis gait of subjects with CP: good inter-session reliability, predictor of postoperative kinematic improvement, minimal clinical threshold calculated at 1.6°, significant relationship with clinical data (joint contractures), and sensibility to change after a single-event multilevel surgery.

Interventions

OTHERGait Profile Score

Gait Profile Score in degrees, calculated from kinematic raw data with the Gdi\_GPS\_calculator spreadsheet developed by Baker (2009).

OTHERGait Visual Score

Gait Visual Score in degrees, calculated from kinematic raw data with the Gdi\_GPS\_calculator spreadsheet developed by Baker (2009)

Sponsors

Centre Hospitalier Universitaire de Saint Etienne
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
6 Years to 18 Years
Healthy volunteers
No

Inclusion criteria

* Etiology of cerebral palsy * Unilateral, bilateral, triplegic or quadriplegic forms of cerebral palsy. * 6 to 18 years old * GMFCS (Gross Motor Function Classification System) I to III * Instrumented gait analysis of the laboratory of St-Etienne * Absence of botulinum toxin injection or serial casting in the three months after a first instrumented gait analysis.

Exclusion criteria

* Etiology others than cerebral palsy as defined classically (ex: ischemic infarcts in a child older than two years). * Previous surgery in lower-limb.

Design outcomes

Primary

MeasureTime frameDescription
Degrees of Gait Profile Score overallDay 1Analyze Degrees of Gait Profile Score overall

Secondary

MeasureTime frameDescription
Gait Profile Score rightMonth 2Analyze Gait Profile Score right.
Gait Profile Score leftYear 2Analyze Gait Profile Score left.

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026