Knee Arthroplasty
Conditions
Keywords
POSTOPERATIVE PAIN, Knee Arthroplasty
Brief summary
Postoperative analgesic treatment methods are applied to patients who have undergone knee arthroplasty. These applications are a routine part of the procedure. It is medically and ethically necessary. Postoperative analgesia applications are started during the intraoperative period and continued during the postoperative period. The analgesia protocol to be used is shaped by the characteristics of the patient and the skill and experience of the anesthesiologist. The scientifically accepted method is multimodel analgesia protocols. These protocols cover a wide range from paracetamol to opioids to peripheral and central blocks (methods such as suprainguinal fascia iliac block (SFIP), adductor block (ACB) and infiltration analgesia (IPACK) applied between the posterior elements of the knee and the popliteal artery). Our aim in this study is to evaluate the effects of analgesia protocols applied to patients undergoing knee arthroplasty surgery on inflammatory biomarkers (such as neutrophil lymphocyte ratio (NLR), platelet lymphocyte ratio (PLR), systemic immune inflammation score (SII), lactate) obtained from routine blood and blood gas examinations in the first 24 hours of the postoperative period.
Interventions
OTHERPeripheral nerve block methods
We apply different nerve blocks to patients for analgesic purposes after knee replacement surgery. These blocks are a combination of SFIP block and adductor channel block and iPACK block.
Sponsors
Senay Canikli
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* 18-75 years old * ASA I,II,III patients * Patients who will undergo elective surgery
Exclusion criteria
* Patients undergoing emergency surgery * Patients with bleeding diathesis * Those who are allergic or sensitive to local anesthetics and opioid drugs, * Those who use gabapentinoids * Patients with neurocognitive disorders, * Patients with chronic organ failure, * Mothers with suspected pregnancy, pregnant or breastfeeding mothers * Patients using opioids * Those who use steroids * Those with a history of substance use
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative pain | postoperative 24 hours | Pain levels of patients will be evaluated with the Numerical Pain Scale (NRS) in the first 24 hours postoperatively. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| inflammatory mediators | preoperative 24 hours | NLR |
Countries
Turkey (Türkiye)
Outcome results
None listed