Stroke
Conditions
Brief summary
The aim of this study is to monitor the daily upper limb movement of persons with stroke, and to relate these quantities to measures of recovery and impairment.
Detailed description
This study is part of The Natural History of Stroke Recovery project. In this study the investigators plan to develop, test and validate an algorithm and software for using Inertial Measuring Units (IMUs) to monitor upper limb daily movement. Then, investigators plan to use this system to monitor such activity in stroke patients. Investigators also plan to develop, test and validate an algorithm and software to test proprioception acuity based on muscle synergy during active and passive movement. Muscle synergy will be determined based on muscles' electrical activity, as measured using surface electromyography (EMG). Investigators will then test the relation between daily movements of the upper limb in stroke patients, and their recovery/impairment levels, including proprioception acuity.
Interventions
None listed
Sponsors
Ben-Gurion University of the Negev
Adi Negev-Nahalat Eran
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
Yes
Inclusion criteria
* \>18 years of age * Independent in all activities of daily living before the stroke. * In- and out-patients at Adi-Negev Nahalat-Eran rehabilitation center. * Medically stable * Able to provide informed consent.
Exclusion criteria
* The presence of any degenerative neurological condition, neuropathy, myopathy or Polio that are not secondary to stroke, excluding diabetic related changes. * Traumatic brain injury and/or extra-cerebral hemorrhage. * Significant psychiatric condition, including alcoholism and drug abuse. * Any severe orthopedic condition (such as amputation or severe pain that limits activity) or chronic pain syndrome.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Hand movements-count | One or two occasions over 1-6 hours each. | The number of hand movements (count) |
| Hand movements-duration | One or two occasions over 1-6 hours each. | The total and average (per hour) time the hands moved, over the tested period. Measured in minutes. |
| Active joint range | One or two occasions over 1-6 hours each. | Maximum, minimum, and mean range of motion of the joints during daily activity. Measured in degrees/radians. |
| Wrist distance | One or two occasions over 1-6 hours each. | The maximum, average and total distance of the wrist from the body during movements. Measured in cm. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Proprioception-3 | One occasions during the first month following recruitment. | Delay between hand movement initiation observed kinematical (acceleration) and kinetically (EMG signal). Measured in msec. |
| Joint range of motion | One or two occasions over 1-6 hours each. | Maximum and minimum joints range of motion (active and passive). Measured in degrees/radians. |
| Synergies | One or two occasions over 1-6 hours each. | Parameters of the correlation (regression) between the kinematic signals of the different upper extremity segments. Including the slope (arbitrary units) and R\^2 (arbitrary units). |
| Fugl-Meyer Assessment (FMA) | One occasions during the first month following recruitment. | Fugl-Meyer Assessment: Motor score of the upper limb is on a 0-66 scale. High score is better. |
| Movement volume | One or two occasions over 1-6 hours each. | Volume occupied by the limb segments calculated using the 3D location of the joints. Measured in cm\^3. |
| Whole body movement time | One or two occasions over 1-6 hours each. | The total and average (per hour) time of movements of the whole body. Measured in minutes. |
| Angular velocity. | One or two occasions over 1-6 hours each. | Maximum and average angular velocity of the joints during daily activity. Measured in degrees/radians per second |
| Action Research Arm Test (ARAT) | One occasions during the first month following recruitment. | Action Research Arm Test Score is on a 0-57 scale. High score is better. |
| Proprioception-1 | One occasions during the first month following recruitment. | The difference between joint angles in an angle matching task. E.g., matching the shoulder angle of a passively moved arm with the contralateral arm. Angles include both anatomical angles and elevation angles. Measured in degrees/radians. |
| Proprioception-2 | One occasions during the first month following recruitment. | Parameters of the correlation (regression) between EMG signals during active and passive movement. Including the constant (in mV), slope (arbitrary units) and R\^2 (arbitrary units). |
Countries
Israel
Contacts
Primary ContactLior Smuelof, PhD
Backup ContactYogev Koren, PhD
Outcome results
None listed