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Health Literacy, Physical and Cognitive Function, Health-related Behaviors, and Quality of Life in COPD

An Investigation of Health Literacy, Physical and Cognitive Function, Health-related Behaviors, and Quality of Life in Chronic Obstructive Pulmonary Disease and Healthy Individuals

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06497816
Enrollment
144
Registered
2024-07-12
Start date
2024-06-15
Completion date
2027-06-15
Last updated
2026-06-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COPD, Health Literacy, Health-Related Behavior

Brief summary

Health literacy is important for controlling disease progression and living a healthy life with illness. High health literacy is associated with higher cognitive performance and lower health-related quality of life. Physical, psychological, and social impairments are seen in chronic obstructive pulmonary disease (COPD). Studies investigating the relationship between health literacy and functional capacity, quality of life, physical activity, cognitive function, health-related behavior, and activities of daily living in individuals with COPD are limited. Therefore, the aim of this study was to compare individuals with COPD with healthy individuals in terms of health literacy, functional capacity, quality of life, physical activity, cognitive function, health-related behavior, and activities of daily living and to investigate the relationship between health literacy and functional capacity, quality of life, physical activity, cognitive function, health-related behavior, and activities of daily living in individuals with COPD.

Interventions

OTHERNo intervention

No intervention

Sponsors

Hacettepe University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
40 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

for the COPD group: * Being over 40 years old, * Diagnosed with COPD and being clinically stable, * Being able to cooperate with the tests to be performed, * Not having any cardiovascular disease, orthopedic or neurological problems that may affect the tests, * Being willing to participate in the study.

Exclusion criteria

for the COPD group: * Being in an acute exacerbation period, * Having any cardiovascular disease, orthopedic or neurological problems that may affect the tests, * Not being willing to participate in the study. Inclusion criteria for the control group: * Being willing to participate in the study and being over 40 years old * Not having any known disease

Design outcomes

Primary

MeasureTime frameDescription
Functional capacity1st dayFunctional capacity assessment using self-paced 6-minute walk test.
Health literacy1st dayTest of Functional Health Literacy in Adults will be used to evaluate health literacy. The TOFHLA is scored on a scale of 0 to 100 and higher scores indicate higher health literacy.
Cognitive function1st dayMontreal Cognitive Assessment will be used to evaluate cognitive function. The Montreal Cognitive Assessment scores range between 0 and 30. A score of 26 or over is considered to be normal.
Health-related behavior1st dayHealth-related Behavior Scale II will be performed to assess health-related behavior. The Health-related Behavior Scale II measures various health-related behaviors and is designed to assess the frequency or extent of engagement in these behaviors. Higher scores of the scale indicate more frequent or healthier behaviors, depending on the specific behavior being measured.
Functional exercise capacity1st dayOne-minute sit to stand test will be performed. The number of repetitions will be recorded.

Secondary

MeasureTime frameDescription
Forced vital capacity1st dayPulmonary function test using a spirometer will be performed. Forced vital capacity will be recorded.
Forced expiratory volume in one second1st dayPulmonary function test using a spirometer will be performed. Forced expiratory volume in one second will be recorded.
forced expiratory volume in one second/forced vital capacity ratio1st dayPulmonary function test using a spirometer will be performed. Forced expiratory volume in one second/forced vital capacity ratio will be recorded.
Peak expiratory flow1st dayPulmonary function test using a spirometer will be performed. Peak expiratory flow will be recorded.
Forced mid-expiratory flow (FEF25-75)1st dayPulmonary function test using a spirometer will be performed. Forced mid-expiratory flow (FEF25-75) will be recorded.
Physical activity level1st dayPhysical activity will be evaluated with International Physical Activity Questionnaire questionnaire. The questionnaire assesses physical activity across different domains, including leisure time, domestic and gardening activities, work-related activities, and transport-related activities. Scores are calculated based on the duration (minutes) and frequency (days) of these activities over the past seven days. Higher scores on the IPAQ indicate a higher level of physical activity.
Assessment of quality of life1st daySt. George quality of life questionnaire will be used to assess quality of life. Higher scores reflect worse health status.
Activities of daily living1st dayActivities of daily living will be evaluated using Leicester Cough Questionnaire. Each question is scored on a scale from 1 (maximum impact) to 7 (minimal impact). An average score is calculated for each domain (physical, psychological, and social), resulting in scores ranging from 1 to 7 per domain, and a total score between 3 and 21. A higher score indicates less impact.

Countries

Turkey (Türkiye)

Contacts

CONTACTAslihan Cakmak-Onal, PhD, PT
aslihancakmak90@gmail.com03123051576
CONTACTElif Kocaaga, MSc, PT
elifkocaaga86@gmail.com
PRINCIPAL_INVESTIGATORAslihan Cakmak-Onal, PhD, PT

Hacettepe University

STUDY_DIRECTORDeniz Inal-Ince, PhD, PT

Hacettepe University

PRINCIPAL_INVESTIGATORElif Kocaaga, MSc, PT

Hacettepe University

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 26, 2026