General Anesthesia, Prostate Cancer Stage, Uterine Myoma
Conditions
Brief summary
It is important to decrease the remifentanil dose for general anesthesia maintenance when using remimazolam. We will evaluate the effect of binaural sound on general anesthesia maintenance with remimazolam infusion.
Interventions
PROCEDUREBinaural sound
Binaural sound: Binaural sound will be applied.
Sponsors
Gangnam Severance Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Patients scheduled for general anesthesia 2. Patients aged 20-60 3. Patients with American Society of Anesthesiologist physical status classification 1-2 4. Patients with ideal body weight 50-80 kg
Exclusion criteria
1. Patients with hearing disability 2. Patients using opioids or sedatives in 1 week 3. Patients who are dependent for alcoholics or drugs 4. Patients with hypersensitivities to remimazolam or remifentanil 5. Patients with arrhythmia, cardiovascular disease, heart failure, or hypovolemia 6. Patients with liver failure
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Intraoperative remifentanil dose | At anesthesia day 0 | Intraoperative remifentanil dose will be measured at anesthesia day 0. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Intraoperative remimazolam dose | At anesthesia day 0 | Intraoperative remimazolam dose will be measured at anesthesia day 0. |
| Pain score (0:no pain, 10:maximal pain) | At anesthesia day 0 and 1 | Pain score (0:no pain, 10:maximal pain) will be measured at anesthesia day 0 and 1. |
| Electroencephalography | At anesthesia day 0 | The relative power of alpha, beta, delta, gamma, and theta band in electroencephalography will be measured at anesthesia day 0. |
Countries
South Korea
Contacts
Primary ContactHyun-Chang Kim
Outcome results
None listed