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Evaluation of U-AKIpredTM for Predicting AKI in Critically Ill Patients Within 12 Hours: a Multicenter Prospective Cohort Study

Evaluation of U-AKIpredTM for Predicting AKI in Critically Ill Patients Within 12 Hours: a Multicenter Prospective Cohort Study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06496555
Enrollment
2100
Registered
2024-07-11
Start date
2024-06-01
Completion date
2025-12-31
Last updated
2024-07-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

External Effectiveness Validation of Model

Brief summary

The goal of our study is to evaluate U-AKIpredTM for predicting AKI in critically ill patients within 12 h by the multicenter prospective cohorts. AKI was diagnosed by Kidney Disease Improving Global Outcomes (KDIGO) criteria. We designed five aspects including the overall fitting effecience evaluation, calibration curve, quantifying calibration performance, quantifying discrimination performance, quantifying clinical utility to evaluate the external validation model.

Interventions

None listed

Sponsors

Second Affiliated Hospital, School of Medicine, Zhejiang University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* critically ill patients who stayed in ICU for over 24 h; * patients older than 18 years of age.

Exclusion criteria

* patients who admitted in ICU had been diagnosed acute kidney injury; * patients who admitted in ICU had been diagnosed acute kidney disease; * patients who admitted in ICU had been diagnosed chronic kidney disease; * patients who admitted in ICU had performed kidney dialysis; * patients who admitted in ICU had performed kidney transplantation; * Pregnant women.

Design outcomes

Primary

MeasureTime frame
AKI occurrence12 hours

Countries

China

Contacts

Primary ContactTao Sun, Doctor
stzr@zju.edu.cn0571-87783752

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026