Hepatocellular Carcinoma
Conditions
Brief summary
The objective of the study is to investigate the long-term outcomes of minimally invasive liver surgery (robotic vs laparoscopic) for hepatocellular carcinoma patients of stage BCLC 0-A. Data from two tertiary centers for liver surgery will be retrospectively reviewed. Patients will be divided in two cohorts (robot; laparoscopy). The primary endpoint will be recurrence-free and overall survival; secondary endpoints were incidence, pattern, and treatment of recurrences.
Interventions
PROCEDUREMinimally invasive liver resection
Patients underwent liver resection either by robotic or laparoscopic approach
Sponsors
Ente Ospedaliero Cantonale, Bellinzona
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Patients undergoing robotic and laparoscopic resections * Histology-confirmed HCC of stage BCLC 0-A * Preserved liver function (Child score A-B) * Patients \>18 years old
Exclusion criteria
* Hand-assisted procedures * Non-elective surgery * Intraoperative switch to locoregional therapies (like radiofrequency or microwave ablation) * Non-histologically confirmed HCC * Mixed hepato-cholangiocarcinoma.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Recurrence-free survival | From the date of liver resection until the first documented HCC progression on follow-up imaging, assessed up to 116 months. The Minimum follow-up accepted was of 3 months postoperatively. | Recurrence was dated at the first HCC detection on follow-up imaging. |
| Overall survival | From the date of liver resection until the date of death for any cause or the last follow-up available whichever came first, assessed up to 116 months. The Minimum follow-up accepted was of 3 months postoperatively. | — |
Outcome results
None listed