Skip to content

Postoperative Anxiety and Depression Among Older Chinese Patients

Postoperative Anxiety and Depression Among Older Chinese Patients: A Prospective Observational Study Based on a Multi-center Perioperative Database in China

Status
Withdrawn
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06495840
Enrollment
0
Registered
2024-07-11
Start date
2020-04-01
Completion date
2022-04-30
Last updated
2026-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anxiety, Depression, Elderly Patients, Non-cardiac Surgery

Brief summary

A multicenter, prospective observational study to describe the socioeconomic characteristics and the occurrence of postoperative anxiety and depression in the Chinese old population.

Detailed description

As China's population ages, the proportion of elderly people undergoing surgery increases. Perioperative anxiety and depression, particularly in elderly patients, is common and associated with multiple medical and social adversities. Previous studies have found a 31 percent risk of anxiety and 29 percent risk of depression in older perioperative patients. However, nationally representative epidemiological data for postoperative anxiety and depression, in particular elderly patients undergoing non-cardiac surgery, are unavailable in China. Therefore, providing nationwide epidemiological data on postoperative anxiety and depression in Chinese elderly patients provides a valuable opportunity for policy makers and health care professionals to optimize the management of geriatric mental health in China.

Interventions

OTHERno intervention

no intervention

Sponsors

Chinese PLA General Hospital
Lead SponsorOTHER
Beijing Tiantan Hospital
CollaboratorOTHER
Peking University First Hospital
CollaboratorOTHER
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
CollaboratorOTHER
Xiangya Hospital of Central South University
CollaboratorOTHER
Beijing Anzhen Hospital
CollaboratorOTHER
Central South University
CollaboratorOTHER
Peking University People's Hospital
CollaboratorOTHER
Zhejiang University
CollaboratorOTHER
Fudan University
CollaboratorOTHER
Sun Yat-sen University
CollaboratorOTHER
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
CollaboratorOTHER
China-Japan Friendship Hospital
CollaboratorOTHER
The Affiliated Hospital Of Guizhou Medical University
CollaboratorOTHER
First Affiliated Hospital of Xinjiang Medical University
CollaboratorOTHER
First Affiliated Hospital of Guangxi Medical University
CollaboratorOTHER
Taihe Hospital
CollaboratorOTHER
Zhejiang Provincial People's Hospital
CollaboratorOTHER
Shanghai Zhongshan Hospital
CollaboratorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No

Inclusion criteria

1. elderly patients (age ≥ 65 years) 2. undergoing elective surgery with a planned overnight hospital stay following surgery 3. non-cardiac surgery, non-neurosurgical surgery

Exclusion criteria

1. patients fully refused to participate in the study 2. patients with severe dementia, language disorder, severe hearing or visual impairment, coma, and end-stage status 3. patients whose surgeries were canceled 4. history of previous severe mental illness or long-term use of psychotropic medications 5. patients admitted to ICU immediately after surgery 6. patients who died within 7 days after surgery 7. patients who did not complete the scale assessment

Design outcomes

Primary

MeasureTime frameDescription
Anxietywithin 7 days after surgeryThe GAD-7 is a seven-item questionnaire for screening on the presence of generalized anxiety disorder and assessing its severity. Items were scored on a four-point scale with total scores ranging from zero to twenty-one. Scores were defined as: ≥5 mild, ≥10 moderate, and ≥15 severe anxiety. The recommended screening cutoff was ≥10, corresponding with at least a moderate level of anxiety. Higher scores mean more anxiety.
Depressionwithin 7 days after surgeryPrimary outcomes were depression Patient Health Questionnaire 9 (PHQ-9).The PHQ-9 is a nine-item questionnaire for screening on the presence of depressive symptoms and monitoring depression severity. Items were scored on a four-point scale with total scores ranging from zero to twenty-seven. Scores were defined as: ≥5 mild, ≥10 moderate, and ≥15 severe level of depression. The recommended screening cutoff was ≥10, corresponding with at least a moderate level of depression. The higher the score, the worse the situation. The total score ranges from 0 to 27, and higher scores indicate more depressive symptoms.

Countries

China

Contacts

STUDY_CHAIRWeidong Mi, PhD

Chinese PLA General Hospital

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Aug 27, 2026