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Results of Cross-leg Free Vascularized Fibular Graft

Long Term Results of Cross-leg Free Vascularized Fibular Transfer for Reconstruction of Complex Post-traumatic Tibial Bone Defects: a Case Series Study

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06491316
Enrollment
22
Registered
2024-07-09
Start date
2024-07-20
Completion date
2024-10-30
Last updated
2024-07-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tibial Fractures

Keywords

Cross-leg flap, Vascularized fibular transfer, Open grade III tibial fractures

Brief summary

This study aims to evaluate the new technique of cross-leg vascularized fibular graft for reconstruction of post-traumatic long tibial bone defects in terms of restoring normal anatomy and function of the traumatized limb in a series of cases admitted in Assiut University hospital, Orthopedics and trauma surgery department.

Detailed description

Reconstruction of post-traumatic long tibial bone defects is still a major therapeutic challenge faced by orthopaedic surgeons on both anatomical and functional concerns, and it is usually associated with significant long-term morbidity. Historically, Amputation was the treatment of choice for long tibial bone defects because of difficulty of reconstructove management of such cases. Over the last few decades, Limb salvage procedures have been developed. During the second world war, massive cancellous bone autograft has been the preferred treatment. But traditional bone graft procedures in many cases may be limited by uncontrollable graft resorption. To overcome this disadvantage different management options have been developed to address bone defects of various lengths as vascularized fibular grafts, Ilizarov technique using bifocal or trifocal bone transport, acute limb shortening and masquelet procedure. However, In some cases long bone defects are associated with extensive soft tissue lacerations together with poor ipsilateral blood supply. For those cases previous surgical options are associated with many complications and may end up with failure of reconstruction and amputation, in this situation cross-leg vascularized fibular graft may be a good treatment option because it can provide a blood supply away from that of the extensively traumatized limb.

Interventions

None listed

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

\- Patients who were admitted into Assiut University Hospital, Orthopedics and Trauma Surgery department with big tibial bone defects ranging from 12 cm to 26 cm, associated with extensive soft tissue damage and poor ipsilateral blood supply confirmed by CT angiography and treated with cross-leg free vascularized fibular graft.

Exclusion criteria

* Patients with bilateral extensive soft tissue damage and poor blood supply. * Patients with medical conditions preventing them from general anesthesia for long periods (\>10 hours).

Design outcomes

Primary

MeasureTime frameDescription
Number of cases of Flap survival6 weeks from operationFlap intake and vascularization without necrosis
Number of cases of Bone healing1 year from operationRadiological evaluation

Secondary

MeasureTime frameDescription
Number of cases with accepted Limb alignment1 yearLong film x-ray of both lower limbs to assess bone alignment

Countries

Egypt

Contacts

Primary ContactMahmoud M Saad, MBBCh
Mahmoud.20134331@med.aun.edu.eg00201060039941
Backup ContactOmar A Refai, Lecturer
omarrefai@aun.edu.eg00201003412298

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026