Weight Gain
Conditions
Brief summary
Volunteers will be divided into two groups which are protein and oil supplement group and normal dietary group. For protein and oil supplement group, they will take 1 sachet of product replaced dinner every day for 8 weeks. For normal dietary group, they will take regular dinner every day for 8 weeks. Weight, body mass index, body composition, waist and hip circumference, skin fold thickness, and chemistry in blood will be evaluated.
Interventions
DIETARY_SUPPLEMENTProtein and oil supplement
Take 1 sachet/day replaced dinner
Sponsors
Mae Fah Luang University
Chulalongkorn University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
DOUBLE (Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* Age 18-60 years * Body mass index more than 23 kg/m2 * No heart disease, diabetes mellitus, thyroid disease, cancer, liver and kidney diseases * Wiling to attend the study
Exclusion criteria
* Allergic to protein, grains, guar gum * Take medicine, supplement, herbal substance for weight control within 1 month * During intermittent fasting * Take birth control pill, steroids, anti-depressant drugs, and anti-epilepsy drugs * Cushing syndrome's * Pregnancy and lactation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Weight | 8 weeks | Weight of volunteers (kg) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Percentage of body fat | 8 weeks | Percentage of body fat (%) using bioelectrical impedance analysis (BIA) |
| Percentage of visceral fat | 8 weeks | Percentage of visceral fat (%) using bioelectrical impedance analysis (BIA) |
| Percentage of subcutaneous fat | 8 weeks | Percentage of subcutaneous fat (%) using bioelectrical impedance analysis (BIA) |
| Percentage of muscle | 8 weeks | Percentage of muscle (%) using bioelectrical impedance analysis (BIA) |
| Waist Circumference | 8 weeks | Waist Circumference (cm) |
| Hip Circumference | 8 weeks | Hip Circumference (cm) |
| Skin fold thickness | 8 weeks | Skin fold thickness (mm) using Skinfold Caliper |
| Total cholesterol | 8 weeks | Blood total cholesterol (mg/dL) |
| Low density lipoprotein | 8 weeks | Low density lipoprotein (mg/dL) in blood |
| High density lipoprotein | 8 weeks | High density lipoprotein (mg/dL) in blood |
| Triglycerides | 8 weeks | Triglycerides (mg/dL) in blood |
| Body mass index | 8 weeks | Body mass index of volunteers (kg/m2) |
| Hemoglobin A1C | 8 weeks | Hemoglobin A1C (%) in blood |
| Total protein | 8 weeks | Total protein (g/dL) in blood |
| Hemoglobin | 8 weeks | Hemoglobin (g/dL) in blood |
| SIRT1 (NAD-dependent deacetylase sirtuin-1) | 8 weeks | SIRT1 (NAD-dependent deacetylase sirtuin-1) (%) in blood |
| 8-hydroxy-2-deoxyguanosine | 8 weeks | 8-hydroxy-2-deoxyguanosine (%) in blood |
| Blood urea nitrogen | 8 weeks | Blood urea nitrogen (mg/dL) in blood |
| Creatinine | 8 weeks | Creatinine (mg/dL) in blood |
| Aspartate transaminase | 8 weeks | Aspartate transaminase (U/L) in blood |
| Alanine aminotransferase | 8 weeks | Alanine aminotransferase (U/L) in blood |
| Alkaline phosphatase | 8 weeks | Alkaline phosphatase (U/L) in blood |
| Fasting blood sugar | 8 weeks | Fasting blood sugar (mg/dL) in blood |
Outcome results
None listed