Health, Subjective
Conditions
Brief summary
Volunteers will be divided into 4 groups which are mulberry leaf extract 6 mg capsule, mulberry leaf extract 12 mg capsule, mulberry leaf extract 18 mg capsule, and placebo capsule group. They will be tested blood glucose levels (taken from the fingertips) before starting. Then, they will take 1 capsule of the sample one time. After taking the sample for 30 minutes, they will take 50 g of sucrose in 250 ml of water in 5 minutes. Then, they will be tested blood glucose levels (taken from the fingertips) at 30, 60, 90, and 120 minutes.
Interventions
DRUGMulberry leaf extract 6 mg capsule
Take one capsule of the sample one time.
DRUGMulberry leaf extract 12 mg capsule
Take one capsule of the sample one time.
DRUGMulberry leaf extract 18 mg capsule
Take one capsule of the sample one time.
DRUGPlacebo capsule
Take one capsule of the sample one time.
Sponsors
Mae Fah Luang University
Chulalongkorn University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SCREENING
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* Age 18-60 years * No diabetes mellitus * Have blood glucose less than 126 mg/dL * Wiling to attend the study
Exclusion criteria
* Take steroids, psychiatric medicine, thiazide diuretic medicine, and beta blocker medicine within 2 weeks before starting of the study * Take dietary supplement, herbal substance, and weight-loss medicine within 2 weeks before starting of the study * Uncontrolled diseases * History of gastrointestinal tract surgery * Liver and Kidney diseases * Pregnancy and lactation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Blood glucose | 120 minutes | Volunteers will be measured the blood glucose using blood glucose meter and strip (accuchek) before and after taking the sample for 30, 60, 90, and 120 minutes. |
Outcome results
None listed