Wrinkle
Conditions
Brief summary
This study aimed to evaluate efficacy and safety of 675-nm laser for dorsal hand rejuvenation in Thai patients. Twenty-six subjects aged 50 to 65 years diagnosed with wrinkle and solar lentigines on both dorsums of hands were included and treated with RedTouch for 3 times every 4 weeks. Then, they were follow up at 3 and 6 months after the final treatment. The measurement of 5-point Global Aesthetic Improvement Scale scores by physicians and subjects were conducted. Moreover, pigmentation level, wrinkle and texture were also recored using Antera. Elasticity was measured using Cutometer.
Detailed description
RedTouch parameter included Moveo, power 5 W, Energy/DOT 500 mJ/DOT, then Standard, power 4 W, spacing 2000 μm, 1 pass per side.
Interventions
DEVICERedtouch
675-nm laser
Sponsors
Mahidol University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
50 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* Subjects diagnosed with wrinkles and solar lentigines on both dorsum of hands
Exclusion criteria
* Pregnant or lactation * Sugjects with a history of allergy to near-infrared wavelength or photosensitizing agents * Subjects who have been treated with any kind of energy-based device on both dorsum of hands 6 months prior to the inclusion * Subjects who have been injected with filler, or platelet-rich plasma on both dorsum of hands on their faces 6 months prior to the inclusion * Active skin infections * History of hypertrophic scars or keloids
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The change in pigmentation level, wrinkle and texture | Baseline, 4, 8, 12 weeks after the first treatment and 3, 6 months after the last treatment | Using Antera® |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The change in elasticity | Baseline, 4, 8, 12 weeks after the first treatment and 3, 6 months after the last treatment | Using Cutometer® |
| Overall improvement by physicians and patients | 4, 8, 12 weeks after the first treatment and 3, 6 months after the last treatment | 5-point GAIS |
| Adverse events | 4, 8, 12 weeks after the first treatment and 3, 6 months after the last treatment | Side effects |
| Pain score | Baseline, 4, 8, 12 weeks after the first treatment | Visual analog scale (0-10; no pain-worst pain possible) |
Contacts
Primary ContactWoraphong Manuskiatti, MD
Backup ContactSupisara Wongdama, MD
Outcome results
None listed