Acute Kidney Injury, Blood Transfusion, Cardiac Disease
Conditions
Keywords
Cardiopulmonary Bypass, Cardiac Surgery, Transfusion, Acute Kidney Injury, ACTA PORT
Brief summary
In the scope of this study, it will be determined whether the ACTA-PORT (Association of Cardiothoracic Anesthetists perioperative risk of blood transfusion) scoring system can predict the incidence of events in other organ systems, and the feasibility of conducting multiple assessments using a single simple score will be investigated.
Detailed description
ACTA-PORT (Association of Cardiothoracic Anesthetists perioperative risk of blood transfusion) score is a simple, reliable, and validated tool used to predict the risk of transfusion in patients undergoing heart surgery. In calculating ACTA-PORT score, age, gender, hemoglobin, body surface area, EuroSCORE, creatinine, and type of operation are used. In this study, it will be determined whether the ACTA-PORT (Association of Cardiothoracic Anesthetists perioperative risk of blood transfusion) scoring system can predict the incidence of events in other organ systems, and the feasibility of conducting multiple assessments using a single simple score will be investigated. The files of patients undergoing open heart surgery in the cardiovascular surgical operating rooms of Ankara Bilkent City Hospital, along with anesthesia records, transfusion records, and test results identified through the Hospital Information Management System, will be prospectively evaluated. Data will be collected after patients are admitted to the intraoperative and postoperative intensive care unit.
Interventions
None listed
Sponsors
Ankara City Hospital Bilkent
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients over 18 years old * Patients having open heart surgery * Patients undergoing surgery by using cardiopulmonary bypass pump
Exclusion criteria
* Patients under 18 years old * Patients diagnosed with kidney disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| KDIGO AKI Staging | Preoperative (last week before operation) and daily after the operation for 7 days | KDIGO is in the process of developing the Clinical Practice Guideline for Acute Kidney Injury (AKI) and Acute Kidney Disease (AKD). ///// Stage 1: Serum creatinine 1.5-1.9 times baseline or ≥0.3 mg/dl (≥26.5 mmol/l) increase or Urine output \<0.5 ml/kg/h for 6-12 hours ////// Stage 2: Serum creatinine 2.0-2.9 times baseline or \<0.5 ml/kg/h for ≥12 hours /////// Stage 3: Serum creatinine 3.0 times baseline or Increase in serum creatinine to ≥4.0 mg/dl (≥353.6 mmol/l) or Initiation of renal replacement therapy or in patients \<18 years, decrease in eGFR to \<35 ml/min per 1.73 m² or Urine output \<0.3 ml/kg/h for ≥24 hours or anuria for ≥12 hours |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Intensive Care Duration | the duration after surgery up to a month | The duration the patient remains in intensive care unit after surgery |
| Hospital Stay Duration | the duration after surgery up to a month | The duration the patient stays in the hospital after surgery until discharge |
| Mechanical Ventilation Duration | the duration after surgery up to a month | The duration the patient remains intubated from surgery to extubation |
| Complications | the duration after surgery up to a month | Cardiac, Pulmonary, Neurological, Infectious, Thrombotic complications and Presence of MODS (Multiple Organ Dysfunction Syndrome) / SIRS (Systemic Inflammatory Response Syndrome) |
| Reoperation Necessity | the duration after surgery up to a month | The need for reoperation due to bleeding |
| Mortality | the duration after surgery up to a month | If the patient dies within 1 month or not |
Countries
Turkey (Türkiye)
Outcome results
None listed