Epithelial Ovarian Cancer
Conditions
Brief summary
The goal of this observational study is to explore the influence and predictive significance of nutritional risk indicators and inflammatory indicators on postoperative complications and prognosis of patients with epithelial ovarian cancer (EOC). The main question it aims to answer is: Can preoperative nutritional risk and inflammatory indexes predict postoperative complications? Do preoperative nutritional risk and inflammatory indexes better predict the prognosis of patients with epithelial ovarian cancer? Which index is the best predictor of postoperative complications or prognosis for patients?
Interventions
None listed
Sponsors
Qinglei Gao
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Healthy volunteers
No
Inclusion criteria
1. histologically confirmed primary epithelial ovarian, peritoneal, and fallopian tube cancers. 2. patients received comprehensive staged surgery or debulking surgery. 3. available data of laboratory examination within 7 days before the surgery.
Exclusion criteria
1. borderline ovarian tumor. 2. receipt of neoadjuvant chemotherapy. 3. presence of other conditions influencing laboratory data, like hepatitis, kidney disease, autoimmune diseases, infectious diseases, blood disease, etc. 4. concurrent cancer in other organs. 5. absence of surgery or biopsy only. 6. multiple staged surgeries.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative Complications | Within 30 days after surgery | Surgical complications within 30 days after comprehensive staging or cytoreductive surgery recorded according to the Clavien-Dindo grading system |
| Progression-free survival | From the date the patient diagnosed with primary ovarian, fallopian tube, or peritoneal cancer to the date of disease progression or death or last follow-up, whichever occurred first, assessed up to 100 months. | Interval between first diagnosis and first recurrence, death, or last follow-up |
| Overall survival | From the date the patient diagnosed with primary ovarian, fallopian tube, or peritoneal cancer to the date of death or last follow-up, whichever occurred first, assessed up to 100 months. | Interval between first diagnosis and death, or last follow-up |
Outcome results
None listed