Apical Periodontitis
Conditions
Keywords
Clinical Trial, Endodontic Sealer, Periapical healing
Brief summary
The goal of this clinical trial is to conduct an in vivo study that allows to compare the periapical healing process of 3 different sealing cements through CBCT, as well as implement the evaluation of these lesions through volumetric measurements to provide high-level scientific information and thus have the possibility of being applied in the clinical dental practice, in patients attending UNICOC dental clinics between 2023 and 2024. The main question it aims to answer is: * Do bioceramic sealer promote faster periapical healing due to their better sealing capacity and high bio-compatibility? * Are there no differences between endodontic sealers in terms of apical healing? If there is a comparison group: Researchers will compare Bio-C Sealer (Bioceramic sealer) Zinc-oxide eugenol sealer and AH-Plus epoxy resin sealer to evaluate periapical healing after a six months follow-up of conventional endodontic therapy. Coronal permanent restoration must be performed no later than 15 days after endodontic therapy.
Interventions
DRUGZinc-Oxide Eugenol Sealer
Zinc oxide-eugenol sealers have a slow setting time, shrinkage while setting, solubility, and can discolour tooth structure. This sealer group has an advantage in terms of antibacterial activity.It will absorb if extruded into the periradicular tissues.
Dentsply AH Plus Root Canal Sealing Material is a two-component paste/paste root canal sealer based on epoxy-amine resin. The AH Plus sealer shows extremely low shrinkage making it a suitable choice of material to seal the root canal.
DRUGBio-C Sealer
Bio-C® Sealer is a ready-to-use, bioceramic root canal sealer with biologically active ingredients to seal and heal the root canal space. Bio-C Sealer's mechanical and physical properties make it easy to manipulate and seal the canals, while its biological properties and high pH ensure safety and treatment success.
Sponsors
Institucion Universitaria Colegios de Colombia
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* Patients aged 18 to 60 * Patients systemically healthy (ASA I) * Patients that require endodontic therapy for single-rooted teeth with pulp necrosis and apical periodontitis (AP). * CBCT PAI periapical index score 3 or above, with no symptoms at the time of appointment.
Exclusion criteria
*
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Volumetric Periapical Healing | Six months follow-up | Changes of the three-dimensional volume of the periapical lesion of endodontic origin |
Countries
Colombia
Outcome results
None listed