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Boosting Executive Function With Brain Exercise

Rejuvenating the Brain and Boosting Executive Function With Exercise Intervention

Status
Not yet recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06482047
Enrollment
80
Registered
2024-07-01
Start date
2024-07-02
Completion date
2025-04-15
Last updated
2024-07-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sedentary Behavior

Brief summary

The goal of this study is to explore the impact of a 15-minute exercise break on brain function and cognitive performance in a simulated classroom setting. The main questions it aims to answer are: 1. How do short exercise breaks affect executive function in college students? 2. What changes occur in brain connectivity and microcirculation after these exercise breaks? Participants were college students who engaged in sessions of continuous sitting or sitting interspersed with exercise. The study used cognitive tasks and brain imaging techniques to measure the effects. The findings reveal improvements in cognitive performance and brain function, suggesting that short exercise breaks are beneficial in educational contexts.

Interventions

Vigorous-intensity cycling on Ergoline Ergoselect 100

Uninterrupted sitting in a quiet room

Moderate-intensity cycling on Ergoline Ergoselect 100

Sponsors

Liye Zou
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
NONE

Intervention model description

The study used a within-participant cross-over design with pre-and post-test comparisons. Participants completed the three following experimental conditions in pseudo-counterbalanced (cannot be completely counterbalanced given that an odd number of participants - hence, was pseudo-counterbalanced) order (odd number of participants) with at least a 7-day washout period between conditions: (i) 115-minute uninterrupted sitting \[control\]; (ii) 50-minute sitting + 15-minute moderate-intensity cycling + 50-minute sitting \[experimental condition 1\]; (iii) 50-minute sitting + 15-minute vigorous-intensity cycling + 50-minute sitting \[experimental condition 2\]. A familiarization session was completed about three days before the experiment started, during which participants were familiarized with the cognitive assessment and cycling protocols.

Eligibility

Sex/Gender
ALL
Age
18 Years to 25 Years
Healthy volunteers
Yes

Inclusion criteria

-right-handed (how was handedness assessed; i.e., What hand do you write with?) with normal or corrected-to-normal vision and normal color vision

Exclusion criteria

-reported a history of cardiovascular, metabolic, gastrointestinal, neurological, or psychiatric disorders, medical conditions requiring medical care, substance addiction, strict diets (e.g., low- carbohydrate and Mediterranean diet), pregnancy, or lactation.

Design outcomes

Primary

MeasureTime frameDescription
Cognitive function3 weeksThis primary outcome measure is assessed by the modified dual-task Stroop paradigm.
Retinal Vessel Diameter3 weeksRetinal Vessel Diameter is assessed by the fully automated fundus camera.
Brain Connectivity3 weeksBrain connectivity is assessed by the NIRSport2 device

Countries

China

Contacts

Primary ContactLiye Zou, Dr.
liyezou123@gmail.com18823437684

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026