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Strength Training and Muscle Lipids

The Effects of Strength Training on Neuromuscular Function and Muscle Lipids.

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06480747
Acronym
Strength-Lip
Enrollment
14
Registered
2024-06-28
Start date
2024-07-01
Completion date
2024-12-07
Last updated
2025-08-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

exercise, muscle cross-sectional area, intramyocellular lipids, extramyocellular lipids, muscle power, motor unit

Brief summary

The purpose of this study is examine the effects of 8 weeks (3 days/week) of resistance exercise training in children 8 to 10 years of age on muscle strength and power, motor unit activation, and lipid profiles of the vastus lateralis.

Interventions

OTHERResistance exercise training

Participants will strength train via linear periodization resistance exercise training.

Sponsors

National Strength and Conditioning Association
CollaboratorOTHER
University of Kansas Medical Center
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
8 Years to 10 Years
Healthy volunteers
Yes

Inclusion criteria

* Healthy volunteer males and females ages 8 - 10 years.

Exclusion criteria

* No history or ongoing neuromuscular diseases. * No history or ongoing musculoskeletal injuries. * No history or ongoing disease that effects metabolism.

Design outcomes

Primary

MeasureTime frameDescription
Change in muscular power of the leg extensors, as measured with isokinetic strength testing.Baseline, following the intervention (9 weeks)The score will reflect the muscular power of the leg extensors. The higher score, reflects greater muscular strength.

Secondary

MeasureTime frameDescription
Change from baseline in thigh muscle cross-sectional areaBaseline, following the intervention (9 weeks)Scores are measured cross-sectional area from ultrasound images. The higher score, reflects greater muscle size of the leg extensors.

Other

MeasureTime frameDescription
Change from baseline in the fatty acid saturation levels of the extramyocellular lipids of the vastus lateralis, as measure with magnetic resonance spectroscopybaseline, following the intervention (9 weeks)The score will reflect a saturation level of fatty acids in the extramyocellular lipid. The higher score, reflects greater fatty acid saturation.
Change from baseline in the fatty acid saturation levels of the intramyocellular lipids of the vastus lateralis, as measure with magnetic resonance spectroscopybaseline, following the intervention (9 weeks)The score will reflect a saturation level of fatty acids in the intramyocellular lipid. The higher score, reflects greater fatty acid saturation.
Change from baseline in intramyocellular lipids of the vastus lateralis, as measure with magnetic resonance spectroscopybaseline, following the intervention (9 weeks)The score will reflect a concentration. The higher score, reflects more fat in the fibers.
Change in total body lean mass, as measured with bioelectrical impedance analysis.baseline, following the intervention (9 weeks)The score will reflect the lean mass. The higher score, reflects greater lean mass.
Change in total body fat mass, as measured with bioelectrical impedance analysis.baseline, following the intervention (9 weeks)The score will reflect the fat mass. The higher score, reflects greater fat mass.
Change from baseline in motor unit activation, as measured with surface electromyography decomposition.baseline, following the intervention (9 weeks)The score will reflect the firing rates of recorded motor units. The higher score, reflects greater motor unit activation.
Change from baseline in extramyocellular lipids of the vastus lateralis, as measure with magnetic resonance spectroscopybaseline, following the intervention (9 weeks)The score will reflect a concentration. The higher score, reflects more fat in the fibers.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026