Healthy
Conditions
Keywords
exercise, muscle cross-sectional area, intramyocellular lipids, extramyocellular lipids, muscle power, motor unit
Brief summary
The purpose of this study is examine the effects of 8 weeks (3 days/week) of resistance exercise training in children 8 to 10 years of age on muscle strength and power, motor unit activation, and lipid profiles of the vastus lateralis.
Interventions
Participants will strength train via linear periodization resistance exercise training.
Sponsors
Study design
Eligibility
Inclusion criteria
* Healthy volunteer males and females ages 8 - 10 years.
Exclusion criteria
* No history or ongoing neuromuscular diseases. * No history or ongoing musculoskeletal injuries. * No history or ongoing disease that effects metabolism.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in muscular power of the leg extensors, as measured with isokinetic strength testing. | Baseline, following the intervention (9 weeks) | The score will reflect the muscular power of the leg extensors. The higher score, reflects greater muscular strength. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change from baseline in thigh muscle cross-sectional area | Baseline, following the intervention (9 weeks) | Scores are measured cross-sectional area from ultrasound images. The higher score, reflects greater muscle size of the leg extensors. |
Other
| Measure | Time frame | Description |
|---|---|---|
| Change from baseline in the fatty acid saturation levels of the extramyocellular lipids of the vastus lateralis, as measure with magnetic resonance spectroscopy | baseline, following the intervention (9 weeks) | The score will reflect a saturation level of fatty acids in the extramyocellular lipid. The higher score, reflects greater fatty acid saturation. |
| Change from baseline in the fatty acid saturation levels of the intramyocellular lipids of the vastus lateralis, as measure with magnetic resonance spectroscopy | baseline, following the intervention (9 weeks) | The score will reflect a saturation level of fatty acids in the intramyocellular lipid. The higher score, reflects greater fatty acid saturation. |
| Change from baseline in intramyocellular lipids of the vastus lateralis, as measure with magnetic resonance spectroscopy | baseline, following the intervention (9 weeks) | The score will reflect a concentration. The higher score, reflects more fat in the fibers. |
| Change in total body lean mass, as measured with bioelectrical impedance analysis. | baseline, following the intervention (9 weeks) | The score will reflect the lean mass. The higher score, reflects greater lean mass. |
| Change in total body fat mass, as measured with bioelectrical impedance analysis. | baseline, following the intervention (9 weeks) | The score will reflect the fat mass. The higher score, reflects greater fat mass. |
| Change from baseline in motor unit activation, as measured with surface electromyography decomposition. | baseline, following the intervention (9 weeks) | The score will reflect the firing rates of recorded motor units. The higher score, reflects greater motor unit activation. |
| Change from baseline in extramyocellular lipids of the vastus lateralis, as measure with magnetic resonance spectroscopy | baseline, following the intervention (9 weeks) | The score will reflect a concentration. The higher score, reflects more fat in the fibers. |
Countries
United States