Diabetes, Dyslipidemias, Hypertension, Obesity
Conditions
Brief summary
The prevalence of chronic diseases is increasing globally. In recent years, intermittent fasting has emerged as an effective dietary pattern against some of the most common chronic diseases in the elderly, alongside the Mediterranean diet. The objective was to determine whether a 12-hour daily intermittent fasting regimen combined with a Mediterranean diet can improve analytical and anthropometric values in the elderly. A total of 17 individuals of both sexes, over 60 years old, autonomous, and with preserved cognitive capacity participated. They were randomly divided into two groups: 8 people in the intervention group performed intermittent fasting along with a Mediterranean diet, and 9 in the control group adopted only a Mediterranean diet. The intervention lasted 3 months, with measurements taken at the beginning and end of the intervention.
Interventions
OTHERTime Restricted Feeding
8 participants who practiced a 12/12 TRF (12 hours of fasting, from approximately 20:30 to 8:30 the following day).
OTHERMediterranean Diet
A control group consisting of 9 participants who followed a standard Mediterranean diet.
Sponsors
Universidad de Zaragoza
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
61 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Over 60 years of age. * Belong to the Bombarda health centre. * Preserved cognitive capacity. * Autonomy for basic and instrumental activities of daily living. * Ability to follow a TRF and/or adopt a Mediterranean dietary pattern.
Exclusion criteria
* Underweight (BMI \<18.5). * Serious or chronic uncontrolled disease. * Specific treatment that could alter blood and/or anthropometric values. * Poorly controlled type 1 or type 2 insulin-dependent diabetes mellitus. * Present or past episode of eating disorder (ED). * High alcohol consumption.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Biochemical values (mg/dL) | 12 weeks | Basal glucose, High-Density Lipoprotein, Low-Density Lipoprotein, total cholesterol, triglycerides, serum transferrin, urea, uric acid, creatinine. |
| Blood Pressure (mmHg) | 12 weeks | Blood pressure (Systolic blood pressure, diastolic blood pressure) |
| Anthropometric values (kg) | 12 weeks | Weight |
| Anthropometric values (cm) | 12 weeks | Weight, waist circumference, hip circumference. |
| Anthropometric values (kg/m^2) | 12 weeks | Body mass index. |
| Anthropometric index (numerical rating scale) | 12 weeks | Atherogenic index of plasma, waist/hip ratio. |
| Biochemical values (IU/L) | 12 weeks | Alkaline phosphatase, aspartate aminotransferase, alanine aminotransferase, gamma-glutamyltransferase |
| Biochemical values (mg/L) | 12 weeks | C-Reactive Protein |
| Biochemical values (µg/L) | 12 weeks | Serum ferritin |
| Biochemical values (µg/dL) | 12 weeks | Iron |
| Biochemical values (g/dL) | 12 weeks | Albumin |
Countries
Spain
Outcome results
None listed