Interactions Between Environmental Exposures and Gut Microbiota in Early Life

The Mechanism of Interaction Between Arsenic Exposure and Gut Microbiota in Infants During Early Life

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06479928

Enrollment

756

Registered

2024-06-28

Start date

2023-07-01

Completion date

2026-12-30

Last updated

2024-07-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infant Development

Keywords

environmental exposure, gut microbiota

Brief summary

Recruit the mothers and their infants who bron in Peking University People's Hospital from 2023 to 2026, to evaluate the interaction between environmental exposure and gut microbiota.

Interventions

OTHERdelivery mode

Based on delivery mode, we will divide them into two groups, including Cesarean section and Natural delivery.

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

1 Days to 24 Months

Healthy volunteers

Yes

Inclusion criteria

1. Pregnant woman * aged 20-40 years old * natural conception * single pregnancy * gestational age ≥36 weeks 2. Newborn * normal Apgar score * no serious congenital diseases

Exclusion criteria

Design outcomes

Primary

Measure	Time frame	Description
Arsenic levels and Gut microbiota	Pregnancy (12, 24, 36 weeks) and infants (born, 1 week, and 1, 3, 6, 12, 24 months)	Arsenic levels in biological samples; gut microbiota and metabolites in stools.

Countries

China

Contacts

Primary ContactXue Xu, Dr.

xuxue19877182@sina.com010-88324385

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026