The Effect of Active Nutritional Support On Quality Of Life In Patients With Head And Neck Cancer Receiving Radiotherapy

The Effect of Active Nutritional Support On The Incidence Of Mucositis And Quality Of Life In Patients With Head And Neck Cancer Receiving Radiotherapy

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06477341

Enrollment

Registered

2024-06-27

Start date

2023-01-01

Completion date

2025-09-01

Last updated

2025-09-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Head and Neck Neoplasms

Brief summary

note effect of appropriate nutrition on head and neck cancer patients receiving radiotherapy

Detailed description

Head and neck cancer (HNC) is the sixth most common cancer worldwide with more than half a million new cases diagnosed each year . Because of the limitations imposed by the complicated anatomical structure of the head and neck to the operation, radiotherapy (RT) has become the main treatment method for HNC. However, damage to the normal tissue surrounding the tumor is inevitable. The most common manifestations of injury caused by RT are mucositis with the dry mouth, loss of taste, and dysphagia. The severe dysphagia leads to a definitive total impossibility of eating through the mouth in 20-30% of patients. Radiation-induced oral mucositis (RIOM) is a common side effect after radiotherapy (RT) in head and neck cancer (HNC) patients. RIOM patients with severe pain have difficulty in eating, which increases the incidence of malnutrition and affects patients' quality of life and the process of RT.

Interventions

DIETARY_SUPPLEMENTvarious available nutrition as those contain high protein content as ensure milk

note effect with usually prescribed suitable oral and parenteral nutrition for head and neck cancers receiving radiotherapy

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SUPPORTIVE_CARE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* head and neck cancer patients with age \>18 * Newly diagnosed head and neck cancer patients * histological proven HNC cancer * head and neck cancer patients treated with radiotherapy or chemo radiotherapy

Exclusion criteria

* Advanced and Metastatic head and neck cancer patients * head and neck cancer patients treated with chemotherapy only

Design outcomes

Primary

Measure	Time frame	Description
nutritional status of patients	two years	Follow up improvement by evaluating weight in kg and height in meters to calculate body mass index in kg / m\^2

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026