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The Effects of L-arginine Supplementation on Anaerobic Exercise Performance

The Effects of L-arginine Supplementation on Anaerobic Exercise Performance

Status
Recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06475391
Enrollment
20
Registered
2024-06-26
Start date
2024-06-14
Completion date
2024-12-31
Last updated
2024-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Human Performance, Skeletal Muscle

Brief summary

The purpose of this study is to evaluate if acute ingestion of L-arginine will enhance anaerobic exercise performance in young, healthy, and recreationally active adults.

Detailed description

After being enrolled in the study you will be measured on a number of parameters including: body circumferences, body composition via bioelectrical impedance analysis (BIA), height, weight, resting blood pressure, and resting heart rate. All participants will be asked to complete the same protocol for this study. The study design is a randomized, double-blind, placebo controlled, cross-over type of study. What this means is that each participant in the study will complete two exercise sessions after ingesting either a placebo (dextrose - a sugar molecule) or the active ingredient \[insert supplement\] plus dextrose. Neither you nor the research assistant testing you on the exercise sessions will know which ingredient you are ingesting before each exercise trial (i.e., the double-blind portion of the study). We will also randomize the order of which supplement plus placebo or placebo alone you will ingest so neither you nor the research assistant testing will know this either. The cross-over part of the study is that you will complete 2 testing sessions to assess some physical performance variables (grip strength, jump height and power, and anaerobic energy system power output) with one-week of a wash-out period between them. This will allow us to compare the placebo session to the active nutritional supplement plus placebo condition to evaluate if the supplements improve exercise performance acutely. You will also be asked to fill in a 24-hour food and fluid log for the period before your initial exercise test. Then you will be asked to repeat this food and fluid intake when completing the second session. No caffeine, alcohol, or vigorous exercise will be allowed for the 24-hours prior to each trial.

Interventions

DIETARY_SUPPLEMENTL-arginine

2 grams iof L-arginine will be ingested before an acute testing bout of exercise tasks in 250 mL of cranberry juice.

DIETARY_SUPPLEMENTPlacebo

Placebo

Sponsors

University of Manitoba
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 39 Years
Healthy volunteers
Yes

Inclusion criteria

* Recreationally physically active individuals will be recruited for the study. In this context it means all participants perform 1-hour of exercise per day over 3-days per week at a minimum for 1-month. All participants will be between the ages of 18-39 years of age.

Exclusion criteria

*

Design outcomes

Primary

MeasureTime frameDescription
Grip Strength5 minutesGrip strength measurement in kilograms of force produced on a hand held dynamometer.
Counter movement vertical jump3 minutesCounter movement vertical jump performance height in centimeters.
Wingate anaerobic cycle ergometer test30 secondsMaximum pedaling power output for 30 seconds of all-out sprinting on a cycle ergometer.

Countries

Canada

Contacts

Primary ContactStephen M Cornish, PhD
Stephen.Cornish@umanitoba.ca204-381-7296
Backup ContactMikal Thrones, BSc
thronesm@myumanitoba.ca

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026