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Association Between Preoperative Hyperglycemia and Postoperative Delirium in Geriatric Hip Fracture Patients

Association Between Preoperative Persistent Hyperglycemia and Postoperative Delirium in Geriatric Hip Fracture Patients

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06473324
Enrollment
2031
Registered
2024-06-25
Start date
2023-11-21
Completion date
2024-01-03
Last updated
2024-06-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hip Fractures, Hyperglycemia, Postoperative Delirium

Brief summary

This retrospective study aims to collect electronic medical record data from Dandong central hospital spanning from January 2013 to November 2023. The collected data does not contain any personally identifiable information or breach privacy. Additionally, this study design does not involve active intervention measures or patient recruitment. The research aims to investigate the correlation between preoperative blood glucose levels in elderly hip fracture patients and postoperative delirium.

Detailed description

A retrospective observational study is planned to explore specific phenomena or associations using electronic medical record data. The collected data does not contain any personally identifiable information or compromise privacy. Additionally, this study design does not involve active intervention measures or patient recruitment. The study data is sourced from the electronic medical record system of hospitalized patients and has received approval from the hospital's research center, with ongoing supervision by the hospital's ethics committee. The study aims to investigate the correlation between preoperative blood glucose levels in hip fracture patients and postoperative complications. The retrospective study aims to collect electronic medical record data spanning from January 2013 to November 2023. The data collection process is consistently monitored and verified by the hospital's ethics committee. Throughout the study, adherence to the ethical principles outlined in the 1964 Helsinki Declaration is ensured, and institutional review board (IRB) approval has been obtained for all aspects of the research. The study aims to provide valuable evidence-based medicine for clinical practitioners by examining the relationship between preoperative persistent hyperglycemia in elderly hip fracture patients and postoperative delirium. Furthermore, it seeks to offer clinical insights for early identification and intervention management of high-risk postoperative delirium patients (POD).

Interventions

None listed

Sponsors

Wenbo Ding
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
60 Years to 90 Years
Healthy volunteers
No

Inclusion criteria

1\) Patients who have undergone surgical treatment for hip fractures.

Exclusion criteria

1. Multiple or pathological hip fractures. 2. Emergent surgery. 3. Age below 60 years. 4. Incomplete electronic medical records or preoperative blood glucose levels were assessed fewer than two times. 5. Presence of neurological and psychiatric disorders, except dementia.

Design outcomes

Primary

MeasureTime frameDescription
Number of Participants with Postoperative Deliriumup to 2 monthsPostoperative Delirium (POD) manifests as acute cognitive dysfunction and consciousness disorder, characterized by changes in attention or consciousness that cannot be attributed to pre-existing cognitive impairments. Typical symptoms include hallucinations, delusions, agitated behavior, disordered speech, decreased attention, confusion, unclear consciousness, and disrupted sleep-wake cycles. Moreover, POD typically occurs within the first five days after surgery, particularly within the initial 48 hours, and exhibits significant fluctuations.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 6, 2026