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This Study Assess Some Physiological Parameters, Blood Picture, and Hemodynamic Parameters, Blood Pressure, Respiratory Assess by SPO2, During Different Periods in Laparoscopic Surgery

Physiological and Biochemical Effects of Laparoscopic Anesthesia and Surgery

Status
Not yet recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06473194
Acronym
laparoscopy
Enrollment
60
Registered
2024-06-25
Start date
2024-10-01
Completion date
2026-11-01
Last updated
2024-06-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia Complication, Physiological Parameter

Brief summary

Laparoscopic surgery is widely used now. These benefits included many items, e.g. reducing post-operative pain, cosmetic the result was improved, and the patient also had more satisfaction for the patient and reduced hospital stay. This surgery involved insufflation of gas into the peritoneal cavity, producing pneumoperitoneum, and causing an increase in intra-abdominal pressure. The raised intraabdominal pressure of the pneumoperitoneum, the patient's position alteration, and the absorption of carbon dioxide into the abdomen have a direct effect on causing a change in physiology, especially in the cardiovascular and respiratory systems. These effects, as well as a direct effect of gas insufflation, may have significant effects on the patient especially if the patient has a comorbidity or is elderly.

Detailed description

The objective of this study was to assess the technique used in laparoscopic surgery and their associated complications, including some hematological parameters, (these include blood pictures and liver enzymes), respiratory, (including the inspired and expired tidal volume, oxygen saturation, airway pressure, plateau pressure, and use of PEEP) cardiovascular system (including the systolic, diastolic, and mean blood pressure, heart rate)

Interventions

PROCEDUREgeneral anesthesia drug (like Propofol, esmeron, and ketamin, .effects of pneumoperitoneum

this research will involve the selection of elective cases with ASA class I or II and assessment of patients with respiratory cardiovascular parameters and hematology perioperative

Sponsors

Mohammed Abdulhameed
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE

Intervention model description

describe techniques of laparoscopic procedures. 2. Discuss complications and assessments of patients who undergo laparoscopic procedures. 3. to assess liver function and hematological effects due to laparoscopic surgery 4. cardiovascular and respiratory squeal due to laparoscopic complication is minor compared to open surgery and can be managed rapidly.

Eligibility

Sex/Gender
ALL
Age
20 Years to 60 Years
Healthy volunteers
Yes

Inclusion criteria

1. elective abdominal surgery 2. a healthy, fit person 3. use of general anesthetics 4. use of pneumoperitoneum and CO2 insufflation

Exclusion criteria

1. emergency condition 2. patient with cardiovascular disease

Design outcomes

Primary

MeasureTime frameDescription
blood pressure.during preoperative, 5 minute, intraoperative every five minute with post operative read after one hourblood pressure in mmHg, pulse rate in beat per minute
AST and ALT liver enzymes were measured, by blood samples taken intravenously in the perioperative period5 minute pre-operation and 5 minute postoperativein unit/liter
blood sugar, should measured and assessed with different groups5 minute during pre-operative and 15 minute post- operative periodblood sugar in mg/dl
end-tidal Co2, measured and compared statistically with other parameterperioperatively every 5 minuteEnd-tidal Co2 in CMH2O
pulse rate measured continuously during intra-operative and compared with other hemodynamic parameter5 minute during preoperative, and continue every 5 minute in perioperativelybeat per minute (BPM)

Secondary

MeasureTime frameDescription
measurement of body weightmeasured preoperative period by 5 minute and post-operative during 15 minutein Kg

Contacts

Primary ContactMohammed Ab. younis, PHD
mohammedhameed330@gmail.com009647801870904
Backup Contactwissem H. HMIDA, PROFF.
hmidawissem@gmail.com+21698452331

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026