Exercise
Conditions
Keywords
Chronic Obstructive Pulmonary Disease, Single Limb exercise, resistance training, continous exercise training, high intensity exercise training
Brief summary
COPD presents not only respiratory symtoms but also vascular or muscle dysfunction. Exercise limitation is observed in COPD. Especially, decreased exercise performance related to vascular and fatique in quadriceps muscle. Exercise training is important for aerobic performance increasing. Generally results show exercise training with both lower limb. Increaed arterial stiffness and fatigue are observed in COPD. One leg exercise training result is not enough to highlight these parameters. Three types single leg exercise intervantion will be applied. Exercise capacity, muscle strength, lung function, electromyography, lactate and quality of life will be measured.
Detailed description
Three types single leg exercise intervantion will applied to COPD patients that devided three groups. One leg continuous exercise training will be aplied to one group. One leg HIIT exercise training will be aplied to other group. One leg resistance exercise training will be aplied to the last group. Exercise capacity and muscle strength are assesed. Lung function is measured. Electormyography is recorded. Lactate and quality of life are measured.
Interventions
OTHERsingle leg exercise intervantion in COPD
single leg exercise intervantions 1. high intensity interval training 2. continous exercise training 3. resistance exercise training
Sponsors
Hacettepe University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
SINGLE (Subject)
Intervention model description
three different type one leg exercise intervention are apllied in patients with copd
Eligibility
Sex/Gender
ALL
Age
40 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* COPD patients that applied to physiotherapy * Cooperation for tests * without severe ortopedical and neurological disease * without severe cardiovascular disease * To volunteer for the study.
Exclusion criteria
* have an acute exacerbation or having exacerbation at last month * hypoxemia (PaO2\<55mmHg) * no cooperated to test without volunteer to study having ortophedical and neurological diesase that affecting of tests severe cardiovascular disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| six minute walk test | pre-intervention | six minute walk test in meter |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| one leg cardiopulmonary exercise test | beginning, day 3 | VO2 as ml/kg/min will be recorded from incremental cycle cpet test |
| quadriceps muscle strength assesing (repeated measeure) | beginning day 1 and last day | quadriceps muscle 10 repeated max muscle strength will be recorded at kilogram, |
| isometrics quadriceps muscle strength assesing | beginning day 1 and last day | quadriceps muscle isometric muscle strength will be recorded at kilogram |
| lung function | beginning day 1 and last day | FEV1/FVC ratio in % |
| cardiopulmonary exercise test | beginning day 2 | VO2 as ml/kg/min will be recorded from incremental cycle cpet test |
| arterial stiffness | beginning day 2 and last day | total vascular resitance, augmentation index @ 75 and pulse wave velocity wil be determined arterial stiffness |
| lactate measurement | beginning day 2 and last day | lactate in mmol |
| electromyography measurement | beginning day 2 and last day | precentage of maximum volunteer contraction) %MVC values will be presented muscle fatigue (median frequence) and activation will be shown electromyograpy (EMG) |
| quality of life assesing | beginning day 1 and last day | total score in 0-100 range |
Countries
Turkey (Türkiye)
Contacts
Primary Contactelif kocaaga, Ms
Backup Contactelif kocaaga, Ms
Outcome results
None listed