Dialysis
Conditions
Keywords
dialysis patients, physical activity
Brief summary
Dialysis patients have reduced walking capacity and an important risk of high blood pressure. These complications are associated with a decline in quality of life and increased mortality. The hypothesis of the study is to show that physical activity during the dialysis session in dialyzed patients has a benefit on quality of life, as well as on muscle, cardiovascular and dialysis parameters.
Detailed description
Dialysis patients have reduced aerobic capacity, walking ability, and an increased risk of hypertension. These complications are associated with a decline in quality of life and increased mortality. Since asthenia is too intense after the dialysis session, patients are encouraged to perform physical activity during dialysis sessions. Some studies have shown that physical activity during dialysis can have benefits on quality of life and improve muscle parameters, but without this being clinically significant. Other studies show no benefit. The objective of the study is to explore the benefits of physical activity on quality of life, muscle parameters, and biological and dialysis parameters in a cohort of compliant hemodialysis patients.
Interventions
OTHERphysical activity
Exercising physical activity during dialysis
Sponsors
Centre Hospitalier Intercommunal André Grégoire
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adults aged 18 and over, undergoing chronic hemodialysis at CHI André Grégoire for more than 3 months. * Consent to participate in physical activity during dialysis sessions. * Written informed consent. * Affiliation with a social security system
Exclusion criteria
* Lower limb amputation without a prosthesis. * Non-healed foot wounds. * Hemoglobin \< 8 g/dl. * Patient refusal to participate. * Severe respiratory (oxygen dependence) or cardiac disease (NYHA class 3 or 4, LVEF \< 30%). * Advanced dementia or psychiatric illness impeding cooperation, or refusal to consent. * Non-French speaking patients unable to understand the study. * Patients under guardianship. * Advanced osteoarthritis, recent hip or knee prosthesis (\< 3 months). * Hypotension (BP \< 90/40 mmHg) or hypertension (BP \> 180/110 mmHg). * Fever (temperature \>= 38°C). * Hypoglycemia (fingerstick glucose \< 0.8 g/l) in diabetic patients. * Dyspnea or desaturation in ambient air \< 95%. * COVID-19 symptoms within the last 21 days, positive PCR test, unable to pedal. * Chest pain or unstable angina. * Muscle or joint contraindications to the pedal exerciser as assessed by a physiotherapist
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in the quality of life of patients | 17 weeks | Score of the Short Form-36 (SF36) questionnaire. The SF36 score varies from 0 to 100. A low score reflects a perception of poor health, loss of function, and presence of pain. A high score reflects a perception of good health, an absence of functional deficit and pain. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in muscle parameters | 17 weeks | Score of the Medical research council scale (MRC) |
| Change in nutritional parameters | 17 weeks | Measurement of body mass index (BMI) |
| Change in inflammatory parameters | 17 weeks | measurement of CRP |
| Change in dialysis parameters (KT/V= clearance time/volume) | 17 weeks | measurement of clearance time/volume (KT/V) |
| Change in blood pressure | 17 weeks | Measurement of systolic and diastolic blood pressure |
| Change in heart rate | 17 weeks | measurement of pulse |
| Change in glycemic control | 17 weeks | Levels of albumin |
| Change in lipid profile | 17 weeks | Measurement of total cholesterol, LDL cholesterol, HDL cholesterol, triglycerides |
Countries
France
Contacts
Primary ContactMarion Gauthier
Outcome results
None listed