Knee Arthritis, Knee Osteoarthritis, Knee Pain Chronic
Conditions
Brief summary
Effect of adding Dexamethasone to Infiltration between the Popliteal Artery and Capsule of the Knee Block with ACB in Patients undergoing Total Knee Arthroplasty
Detailed description
Knee arthroplasty is one of the most common orthopaedic procedures, especially in elderly patients, due to the deformation of joints. Patients may complain of severe pain due to surgical trauma and prostheses. Regional anaesthesia methods may be performed to reduce the inflammatory response, opioid consumption, and opioid-related side effects.
Interventions
DRUGRopivacaine
Ultrasound-guided iPACK block + ACB - 2 x (20ml 0,2% ropivacaine + 2ml 0.9% NaCl)
Ultrasound-guided iPACK block + ACB - 2 x (20ml 0,2% ropivacaine + 2mg Dexamethasone)
Sponsors
Poznan University of Medical Sciences
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
65 Years to 100 Years
Healthy volunteers
No
Inclusion criteria
* patients scheduled for total hip arthroplasty * patients aged \>65 and \<100 years * patients able to provide informed consent * patients able to reliably report symptoms to the research team
Exclusion criteria
* inability to provide first-party consent due to cognitive impairment or a language barrier
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Time to first rescue opioid analgesia | 48 hours after surgery | Time after surgery when the patient needs opiate for the first time |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Total Opioid Consumption | 48 hours after surgery | Total opiate consumption after surgery |
| Numerical Rating Scale [range 0:10] | 4 hours after surgery | Postoperative pain assessment will be performed using the NRS score (0 = no pain, 10 = the most severe pain felt) |
| Quadriceps muscle strength assessed using medical research council scale [range 0:5] | 4 hours after surgery | Quadriceps muscle strength (knee extension and hip adduction) will be evaluated according to the medical research council muscle strength rating |
| Nerve damage [range 0-4] | 12 hours after surgery | Nerve damage assesment will be performed using the nerve damage score (N0- no nerve damage; N1- minor - sensory paresthesia; N2- major -complete sensory anesthesia; N3- Complete- complete motor defect with or without paraesthesia; N4-CRPS- Complex Regional Pain Syndrome) |
| glucose | 12 hours after surgery | blood glucose level |
Countries
Poland
Outcome results
None listed