Beta Thalassemia Major
Conditions
Brief summary
respiratory complications are very prevalent in children with beta thalasemia major (BTM), so choosing inspiratory muscle trianing to decrease of prevent it and to improve pulmoanry funntions is important
Detailed description
children patients with BTM accounted 40 children will assigned to a group of inspiratory muscle training or waiting list group. the group will contain twenty children. the group of training will receive two session per day of training by threshold inspiratory muscle trainer ( for six day per week for 12 weeks)
Interventions
BEHAVIORALinspiratory muscle training
children patients with BTM accounted 20 children will receive two session per day of training by threshold inspiratory muscle trainer ( for six day per week for 12 weeks). the session will contain six sets of inspiratory muscle training and the one set will contain five respiratory cycles
Sponsors
Ahram Canadian University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
8 Years to 12 Years
Healthy volunteers
No
Inclusion criteria
* 40 beta thalassemia major children * boys and girls
Exclusion criteria
* respiratory diseases * cardiac diseases renal diseases liver diseases muscle and joint disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| forced expiratory volume t the first second of expiration | it will be assessed after 12 weeks | it will measure pulmonary function |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| six minute walk testing | it will be assessed after 12 weeks | it will measure aerobic capacity |
| forced vital capcity | it will be assessed after 12 weeks | it will measure pulmonary function |
| maximal inspiratory pressure | it will be assessed after 12 weeks | it will measure strength of inspiratory muscles |
| Pediatrics' Quality of Life Inventory (children proxy) | it will be assessed after 12 weeks | it will assess quality of life and filled by children |
| Pediatrics' Quality of Life Inventory (parent proxy) | it will be assessed after 12 weeks | it will assess quality of life and filled by parents of children |
| FEV1/FVC | it will be assessed after 12 weeks | it will measure pulmonary function |
Countries
Egypt
Contacts
Primary Contacthagar el-hadidy, lecturer
Backup ContactShimaa Boundok, lectuerer
Outcome results
None listed