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Comparison of the Mammary Harvesting Technique

Comparison of the Effect of Mammary Artery Harvesting Technique to Sternal Blood Supply Using Non-contact Dynamic Thermography

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06464354
Enrollment
90
Registered
2024-06-18
Start date
2023-06-01
Completion date
2023-12-31
Last updated
2024-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic Heart Disease

Keywords

sternotomy, thermography, coronary bypass, LIMA, skeletonization technique

Brief summary

The skeletonization technique of left internal artery (LIMA) harvesting is reported as more spar-ing to the vascular supply of the sternum. Some studies report a greater length and greater flow of the graft additionally. The aim of our study was to measure the difference in post-op sternal blood supply compared to the pedicle harvesting technique and to measure the length and flow of the LIMA graft.

Detailed description

A total of 90 patients were examined in a prospective randomized study. In 60 patients referred for coronary artery bypass grafting (CABG), LIMA was harvested, one-half (n=30) skeletonized, and one-half (n=30) with a pedicle. Thirty patients operated via sternotomy without LIMA harvesting (other procedures, for instance, valve surgery) were the control group. In patients undergoing LIMA harvest, harvest duration, graft length, and graft free flow were measured at defined arterial pressure. In all patients, the sternal blood flow was examined by active dynamic thermography (DIRT): first preoperatively and on 4th postoperative day. During this, the time of spontaneous rewarming of the skin surface after the application of a cold stimulus was measured in the caudal part of the sternum. The difference between postoperative and preoperative time was calculated and compared between groups.

Interventions

PROCEDUREThe mammary artery harvesting by the pedicle technique

The mammary artery harvesting by the pedicle technique was used in the LIMA pedicle study group.

PROCEDUREThe mammary harvesting using the skeletonization technique

The mammary harvesting using the skeletonization technique was used in the LIMA skeletonized study group.

PROCEDURENo intervention

No intervention was used in the control study group.

Sponsors

University Hospital Ostrava
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum

Inclusion criteria

* Elective cardiac surgery procedure via median sternotomy * The left mammary artery (LIMA) harvesting for coronary bypass planned as a part of the operation - Group 1 and 2 * Other cardiac surgery procedures without the LIMA harvesting (valve surgery for instance) - Control group * Signing of the informed consent

Exclusion criteria

* Emergent surgery * Re-operation * Re-sternotomy * Thoracotomy approach * Harvesting of both mammary arteries (BIMA) * Endocarditis * Ongoing non-cardiac infection * Fever * Circulatory failure * Ongoing administration of catecholamines to patient * Unsigned informed consent

Design outcomes

Primary

MeasureTime frameDescription
Rewarming time differencefirst preoperatively and on 4th postoperative dayDuration of spontaneous rewarming of the skin surface of the caudal sternum after a cold stimulus, measured from 24°C to 27°C. Unit: seconds (s)

Secondary

MeasureTime frameDescription
Duration of the mammary graft harvestingduring surgery, immediately after the graft harvestingTime from the start of the harvesting to complete graft release. Unit: minute (min).
Length of the mammary artery graftduring surgery, immediately after the graft harvestingLength from the distance of the graft from the chest wall to its distal end. Unit: millimeter (mm).
Free outflow of the mammary arteryduring surgery, just before the graft useAfter trimming the distal clip on the graft at an arterial pressure of 70 mmHg, free flow for 30 seconds, then multiplied by two. Unit: millilitre per minute (ml/min).

Countries

Czechia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026